Heart failure (HF) is a complex syndrome with an enormous societal burden in terms of cost,
morbidity, and mortality. Natriuretic peptide testing is now widely used to support diagnosis …

The natriuretic peptides are important tools to establish diagnosis and prognosis in heart
failure (HF). With application of therapies for HF, changes in both B-type natriuretic peptide …

Importance In patients with heart failure and reduced ejection fraction (HFrEF), treatment
with sacubitril-valsartan reduces N-terminal pro–b-type natriuretic peptide (NT-proBNP) …

Heart failure (HF) is a rising epidemic due to the ageing population and progress in all areas
of medicine. Thus, research efforts are made to ensure a timely diagnosis, to improve …

Abstract Background: The GUIDE-IT (GUIDing Evidence Based Therapy Using Biomarker
Intensified Treatment in Heart Failure) trial demonstrated that a strategy to “guide” …

Abstract Objectives: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker
Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy …

Background Lung ultrasound (LUS) can be used to assess pulmonary congestion by
imaging B-lines ('comets') for patients with acute heart failure (AHF). Objectives Investigate …

This study sought to evaluate the potential of circulating long non‐coding RNA s (lnc RNA s)
as biomarkers for heart failure (HF). We measured the circulating levels of 13 individual lnc …

Aims Treatment response to vericiguat, based on baseline N‐terminal pro‐brain natriuretic
peptide (NT‐proBNP) subgroups specified in the protocol, was evaluated in the heart failure …

Background Sacubitril/valsartan is an angiotensin receptor–neprilysin inhibitor indicated for
the treatment of patients with chronic heart failure (HF) with reduced ejection fraction; …