Artificial intelligence in veterinary medicine is an emerging field. Machine learning, a
subfield of artificial intelligence, allows computer programs to analyze large imaging …

Collagen is a major structural component of nearly every tissue in the human body, whose
hierarchical organization imparts specific mechanical properties and defines overall tissue …

Abstract Purpose of Review This review synthesizes recent advancements in understanding
subchondral bone (SCB) biomechanics using computed tomography (CT) and micro …

Subchondral bone structure has been observed to change in osteoarthritis (OA). However, it
remains unclear how the early-stage OA changes affect the mechanics (stresses and …

Osteoarthritis (OA) is a degenerative bone disease associated with aging. The rising global
aging population has led to a surge in OA cases, thereby imposing a significant …

Abstract Characterization of brain infarct lesions in rodent models of stroke is crucial to
assess stroke pathophysiology and therapy outcome. Until recently, the analysis of brain …

Articular calcified cartilage (ACC) has been dismissed, by some, as a remnant of
endochondral ossification without functional relevance to joint articulation or weight …

Concurrent osteoarthritic (OA) manifestations in bone and cartilage are poorly known. To
shed light on this issue, this study aims to investigate changes in subchondral bone and …

High-resolution non-destructive 3D microCT imaging allows the visualization and structural
characterization of mineralized cartilage and bone. Deriving statistically relevant quantitative …

Ethnopharmacological relevance The increasing incidence of osteoarthritis (OA), especially
among the elderly population, highlights the need for more efficacious treatments that go …