Managing hemolyzed samples in clinical laboratories

AM Simundic, G Baird, J Cadamuro… - Critical reviews in …, 2020 - Taylor & Francis
Hemolysis is conventionally defined as membrane disruption of red blood cells and other
blood cells that is accompanied by subsequent release of intracellular components into the …

[HTML][HTML] Methods for hemolysis interference study in laboratory medicine–a critical review

F Marques-Garcia - Ejifcc, 2020 - ncbi.nlm.nih.gov
Hemolysis represents an important source of error associated with the pre-analytical phase.
Improving the protocols for detection, measurement, management of the parameters affected …

[HTML][HTML] Practical recommendations for managing hemolyzed samples in clinical chemistry testing

G Lippi, J Cadamuro, A von Meyer… - Clinical Chemistry and …, 2018 - degruyter.com
We suggest here a pragmatic approach for managing results of clinical chemistry testing in
hemolyzed samples collected from adults/older children, attempting to balance the need to …

[HTML][HTML] Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers …

AK Saenger, AS Jaffe, R Body, PO Collinson… - Clinical Chemistry and …, 2019 - degruyter.com
Two interferences recently brought to the forefront as patient safety issues include hemolysis
(hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry …

[HTML][HTML] Preanalytical quality improvement–an interdisciplinary journey

J Cadamuro, G Baird, G Baumann… - Clinical Chemistry and …, 2022 - degruyter.com
Since the beginning of laboratory medicine, the main focus was to provide high quality
analytics. Over time the importance of the extra-analytical phases and their contribution to …

Erroneous potassium results: preanalytical causes, detection, and corrective actions

K Schlüter, J Cadamuro - Critical Reviews in Clinical Laboratory …, 2023 - Taylor & Francis
Potassium is one of the most requested laboratory tests. Its level is carefully monitored and
maintained in a narrow physiological range. Even slightly altered potassium values may …

A deep learning-based system for assessment of serum quality using sample images

C Yang, D Li, D Sun, S Zhang, P Zhang, Y Xiong… - Clinica Chimica …, 2022 - Elsevier
Background Serum quality is an important factor in the pre-analytical phase of laboratory
analysis. Visual inspection of serum quality (including recognition of hemolysis, icterus, and …

[HTML][HTML] Visual assessment of sample quality: quo usque tandem?

G Lippi, J Cadamuro - Clinical Chemistry and Laboratory Medicine …, 2018 - degruyter.com
Sample hemolysis is conventionally defined as the presence of a variable amount of cell-
free hemoglobin in serum or plasma. The reference (ie “normal”) concentration of free and …

[HTML][HTML] Impact of individualized hemolysis management based on biological variation cut-offs in a clinical laboratory

F Marques-Garcia, DHH Jung… - Annals of Laboratory …, 2022 - synapse.koreamed.org
Background Hemolysis is the most common type of preanalytical interference. Cut-offs
based on the hemolysis index level can be established using different approaches. The …

A reference chart for clinical biochemical tests of hemolyzed serum samples

J Ni, W Zhu, Y Wang, X Wei, J Li, L Peng… - Journal of Clinical …, 2021 - Wiley Online Library
Background Although the effect of hemolysis has been extensively evaluated on clinical
biochemical tests, a practical guidance for laboratory staff to rapidly determine whether a …