Cadmium (Cd) toxicity poses a significant threat to human health and the environment due
to its widespread occurrence and persistence. In recent years, considerable attention has …

Increasing evidence suggests that elevated intracellular levels of reactive oxygen species
(ROS) play a significant role in the pathogenesis of many diseases. Increased intracellular …

Dysregulated inflammation after trauma or infection could result in the further disease and
delayed tissue reconstruction. The conventional anti-inflammatory drug treatment suffers to …

Despite its effectiveness in treating inflammatory diseases and various malignancies,
methotrexate (MTX) is well known to cause hepatotoxicity, which involves increased …

Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by Kelch-like ECH-associated
protein 1 (Keap1) alkylation plays a central role in anti-inflammatory therapy. However …

Background: Chronic obstructive pulmonary disease (COPD) is a progressive and chronic
respiratory disorder characterized by reversible airflow limitation and lung parenchyma …

Introduction Much interest has been addressed to antioxidant dietary supplements that are
known to lower the risk of developing glaucoma or delay its progression. Among them …

Deltamethrin (DM) is a widely used insecticide that has demonstrated developmental toxicity
in the early life stages of fish. To better characterize the underlying mechanisms, embryos …

Idiopathic pulmonary fibrosis (IPF) is the most widely studied interstitial lung disease. IPF
eventually leads to respiratory insufficiency, lung cancer, and death. Carvedilol (CAR) is a …

Oxidative stress is due to an unbalance between pro-oxidants, such as reactive oxygen
(ROS) and nitrogen (RNS) species, and antioxidants/antioxidant system. Under …