Cellular proteins called" restriction factors" can serve as powerful blockades to HIV
replication, but the virus possesses elaborate strategies to circumvent these barriers. First …

The plasma membrane is the final barrier that enveloped viruses must cross during their
egress from the infected cell. Here, we review recent insights into the cell biology of retroviral …

Tetherin (Bst2/CD317/HM1. 24) is an interferon-induced antiviral host protein that inhibits
the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 …

Viral protein U (Vpu) is a type 1 membrane-associated accessory protein that is unique to
human immunodeficiency virus type 1 (HIV-1) and a subset of related simian …

Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired
immunodeficiency syndrome and its infection leads to the onset of several disorders such as …

Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent
enveloped viral particles from the surface of infected cells. However, the mechanisms …

Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …

Abstract Tetherin (BST2/CD317) has emerged as a key host cell defense molecule,
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …

Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced
antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles …

BST2/tetherin, an antiviral restriction factor, inhibits the release of enveloped viruses from
the cell surface. Human immunodeficiency virus-1 (HIV-1) antagonizes BST2 through viral …