The restriction factors of human immunodeficiency virus
RS Harris, JF Hultquist, DT Evans - Journal of Biological Chemistry, 2012 - ASBMB
Cellular proteins called" restriction factors" can serve as powerful blockades to HIV
replication, but the virus possesses elaborate strategies to circumvent these barriers. First …
replication, but the virus possesses elaborate strategies to circumvent these barriers. First …
Host factors involved in retroviral budding and release
J Martin-Serrano, SJD Neil - Nature Reviews Microbiology, 2011 - nature.com
The plasma membrane is the final barrier that enveloped viruses must cross during their
egress from the infected cell. Here, we review recent insights into the cell biology of retroviral …
egress from the infected cell. Here, we review recent insights into the cell biology of retroviral …
Vpu binds directly to tetherin and displaces it from nascent virions
MW McNatt, T Zang, PD Bieniasz - PLoS pathogens, 2013 - journals.plos.org
Tetherin (Bst2/CD317/HM1. 24) is an interferon-induced antiviral host protein that inhibits
the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 …
the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 …
Modulation of HIV-1-host interaction: role of the Vpu accessory protein
Viral protein U (Vpu) is a type 1 membrane-associated accessory protein that is unique to
human immunodeficiency virus type 1 (HIV-1) and a subset of related simian …
human immunodeficiency virus type 1 (HIV-1) and a subset of related simian …
Type I interferon responses by HIV-1 infection: association with disease progression and control
A Soper, I Kimura, S Nagaoka, Y Konno… - Frontiers in …, 2018 - frontiersin.org
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired
immunodeficiency syndrome and its infection leads to the onset of several disorders such as …
immunodeficiency syndrome and its infection leads to the onset of several disorders such as …
Mechanism of HIV-1 virion entrapment by tetherin
S Venkatesh, PD Bieniasz - PLoS pathogens, 2013 - journals.plos.org
Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent
enveloped viral particles from the surface of infected cells. However, the mechanisms …
enveloped viral particles from the surface of infected cells. However, the mechanisms …
Host restriction factors in retroviral infection: promises in virus-host interaction
YH Zheng, KT Jeang, K Tokunaga - Retrovirology, 2012 - Springer
Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …
The antiviral activities of tetherin
SJD Neil - Intrinsic Immunity, 2013 - Springer
Abstract Tetherin (BST2/CD317) has emerged as a key host cell defense molecule,
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …
Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction
A Le Tortorec, S Willey, SJD Neil - Viruses, 2011 - mdpi.com
Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced
antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles …
antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles …
Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1
X Jia, E Weber, A Tokarev, M Lewinski, M Rizk… - Elife, 2014 - elifesciences.org
BST2/tetherin, an antiviral restriction factor, inhibits the release of enveloped viruses from
the cell surface. Human immunodeficiency virus-1 (HIV-1) antagonizes BST2 through viral …
the cell surface. Human immunodeficiency virus-1 (HIV-1) antagonizes BST2 through viral …