Generation, optimization, and application of ultrashort femtosecond pulse in mode-locked fiber lasers

Y Han, Y Guo, B Gao, C Ma, R Zhang… - Progress in Quantum …, 2020 - Elsevier
Ultrafast femtosecond mode-locked fiber laser plays an indispensable role in medical
imaging, space ranging, ophthalmology, terahertz spectroscopy, material micromachining …

Speed scaling in multiphoton fluorescence microscopy

J Wu, N Ji, KK Tsia - Nature Photonics, 2021 - nature.com
After over 30 years of advances, multiphoton microscopy (MPM) is now instrumental in a
wide range of in vivo biological imaging applications. However, it has, until recently …

Two-photon absorption: an open door to the NIR-II biological window?

PA Shaw, E Forsyth, F Haseeb, S Yang… - Frontiers in …, 2022 - frontiersin.org
The way in which photons travel through biological tissues and subsequently become
scattered or absorbed is a key limitation for traditional optical medical imaging techniques …

jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths

MA Mohr, D Bushey, A Aggarwal, JS Marvin, JJ Kim… - Nature …, 2020 - nature.com
Femtosecond lasers at fixed wavelengths above 1,000 nm are powerful, stable and
inexpensive, making them promising sources for two-photon microscopy. Biosensors …

Designing a large field-of-view two-photon microscope using optical invariant analysis

JR Bumstead, JJ Park, IA Rosen, AW Kraft… - …, 2018 - spiedigitallibrary.org
Conventional two-photon microscopy (TPM) is capable of imaging neural dynamics with
subcellular resolution, but it is limited to a field-of-view (FOV) diameter< 1 mm. Although …

Deep reinforcement with spectrum series learning control for a mode-locked fiber laser

Z Li, S Yang, Q Xiao, T Zhang, Y Li, L Han, D Liu… - Photonics …, 2022 - opg.optica.org
A spectrum series learning-based model is presented for mode-locked fiber laser state
searching and switching. The mode-locked operation search policy is obtained by our …

Advances in ultrafast fiber lasers for multiphoton microscopy in neuroscience

T Srinivasan, M Yildirim - Photonics, 2023 - mdpi.com
Multiphoton microscopy (MPM) has emerged as a vital tool in neuroscience, enabling
deeper imaging with a broader field of view, as well as faster and sub-cellular resolution …

Deep-tissue two-photon microscopy with a frequency-doubled all-fiber mode-locked laser at 937 nm

H He, H Tang, M Zhou, H Ming Lai… - Advanced …, 2022 - spiedigitallibrary.org
In two-photon microscopy, low illumination powers on samples and a high signal-to-noise
ratio (SNR) of the excitation laser are highly desired for alleviating the problems of …

All-fiberized 1840-nm femtosecond thulium fiber laser for label-free nonlinear microscopy

D Xu, KN Bourdakos, A Crisford, P Johnson… - Biomedical Optics …, 2023 - opg.optica.org
We report an all-fiberized 1840-nm thulium-fiber-laser source, comprising a dissipative-
soliton mode-locked seed laser and a chirped-pulse-amplification system for label-free …

Multiphoton in vivo imaging with a femtosecond semiconductor disk laser

FF Voigt, F Emaury, P Bethge, D Waldburger… - Biomedical optics …, 2017 - opg.optica.org
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several
applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped …