Glucocorticoid hormones were discovered to have use as potent anti-inflammatory and
immunosuppressive therapeutics in the 1940s and their continued use and development …

Over the last two decades, it has become evident that estrogens preserve the integrity of
energy homeostasis at central and peripheral levels. Estrogen deficiency, such as that …

The thyroid hormone (TH) plays a significant role in diverse processes related to growth,
development, differentiation, and metabolism. TH signaling modulates energy expenditure …

Background: Obesity is often associated with nonalcoholic fatty liver disease (NAFLD),
which refers to a large spectrum of hepatic lesions including fatty liver, nonalcoholic …

Obesity is commonly associated with nonalcoholic fatty liver (NAFL), a benign condition
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …

The presence of brown adipose tissue (BAT) in adults has become increasingly well defined
as a result of functional imaging studies of thermogenically active BAT. Findings from these …

Glucocorticoids (GCs) are hormones that aid the body under stress by regulating glucose
and free fatty acids. GCs maintain energy homeostasis in multiple tissues, including those in …

Long-term glucocorticoid (GC) treatment induces central fat accumulation and metabolic
dysfunction. We demonstrate that microRNA-27b (miR-27b) plays a central role in the …

Metabolic-associated fatty liver disease (MAFLD), which is often linked to obesity,
encompasses a large spectrum of hepatic lesions, including simple fatty liver …

An excess of glucocorticoids leads to the development of obesity in both mice and humans,
but the mechanism for this is unknown. Here, we determine the extent to which decreased …