Big data, big knowledge: big data for personalized healthcare
M Viceconti, P Hunter, R Hose - IEEE journal of biomedical and …, 2015 - ieeexplore.ieee.org
The idea that the purely phenomenological knowledge that we can extract by analyzing
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
Current state of the art MRI for the longitudinal assessment of cystic fibrosis
Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …
[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI
Hyperpolarised 3He ventilation-MRI, anatomical lung MRI, lung clearance index (LCI), low-
dose CT and spirometry were performed on 19 children (6–16 years) with clinically stable …
dose CT and spirometry were performed on 19 children (6–16 years) with clinically stable …
Comparison of 3He and 129Xe MRI for evaluation of lung microstructure and ventilation at 1.5T
Background To support translational lung MRI research with hyperpolarized 129Xe gas,
comprehensive evaluation of derived quantitative lung function measures against …
comprehensive evaluation of derived quantitative lung function measures against …
Feasibility of human lung ventilation imaging using highly polarized naturally abundant xenon and optimized three‐dimensional steady‐state free precession
Purpose To demonstrate the potential for high quality MRI of pulmonary ventilation using
naturally abundant xenon (NAXe) gas. Methods MRI was performed at 1.5 Tesla (T) and 3 T …
naturally abundant xenon (NAXe) gas. Methods MRI was performed at 1.5 Tesla (T) and 3 T …
Spatial fuzzy c‐means thresholding for semiautomated calculation of percentage lung ventilated volume from hyperpolarized gas and 1H MRI
PJC Hughes, FC Horn, GJ Collier… - Journal of Magnetic …, 2018 - Wiley Online Library
Purpose To develop an image‐processing pipeline for semiautomated (SA) and
reproducible analysis of hyperpolarized gas lung ventilation and proton anatomical …
reproducible analysis of hyperpolarized gas lung ventilation and proton anatomical …
[HTML][HTML] Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI
JR Astley, AM Biancardi, PJC Hughes, H Marshall… - Scientific Reports, 2022 - nature.com
Respiratory diseases are leading causes of mortality and morbidity worldwide. Pulmonary
imaging is an essential component of the diagnosis, treatment planning, monitoring, and …
imaging is an essential component of the diagnosis, treatment planning, monitoring, and …
Magnetic resonance imaging with hyperpolarized agents: methods and applications
In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …
development for MRI applications to address the twin challenges of functional and …