Sounding the alarmins—the role of alarmin cytokines in asthma

GM Gauvreau, C Bergeron, LP Boulet, DW Cockcroft… - Allergy, 2023 - Wiley Online Library
The alarmin cytokines thymic stromal lymphopoietin (TSLP), interleukin (IL)‐33, and IL‐25
are epithelial cell‐derived mediators that contribute to the pathobiology and …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases

L Zeng, K Yang, G Yu, W Hao, X Zhu, A Ge… - Cell Death & …, 2024 - nature.com
Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …

IL-33 and IL-37: a possible Axis in skin and allergic diseases

F Borgia, P Custurone, F Li Pomi, M Vaccaro… - International journal of …, 2022 - mdpi.com
Interleukin (IL)-37 and IL-33 are among the latest cytokines identified, playing a role in
several inflammatory conditions, spanning from systemic conditions to tumors to localized …

[HTML][HTML] Interleukin-33/serum stimulation-2 pathway: Regulatory mechanisms and emerging implications in immune and inflammatory diseases

P He, M Wu, L Zheng, Y Duan, Q Fan, X Zhu… - Cytokine & Growth Factor …, 2024 - Elsevier
Abstract Interleukin (IL)− 33, a nuclear factor and pleiotropic cytokine of the IL-1 family, is
gaining attention owing to its important role in chronic inflammatory and autoimmune …

Biological effects of IL-33/ST2 axis on oral diseases: autoimmune diseases and periodontal diseases

M Wang, M Gao, Z Yi - International Immunopharmacology, 2023 - Elsevier
IL-33 is a relatively new member of the IL-1 cytokine family, which plays a unique role in
autoimmune diseases, particularly some oral diseases dominated by immune factors. The IL …

The role of tolerogenic dendritic cells in systematic lupus erythematosus progression and remission

TA Faraj, RK Kheder, HS Abdulabbas… - International …, 2023 - Elsevier
Systematic lupus erythematosus (SLE) is an autoimmune disease reflecting an imbalance
between effector and regulatory immune responses. Dendritic cells (DC) are a link between …

Mast cell involvement in the pathogenesis of selected musculoskeletal diseases

Ł Gutowski, S Kanikowski, D Formanowicz - Life, 2023 - mdpi.com
In recent years, there has been a noteworthy revival of interest in the function of mast cells
(MCs) in the human body. It is now acknowledged that MCs impact a wide array of …

[HTML][HTML] Potential mechanistic roles of Interleukin-33 in rheumatoid arthritis

T Ouyang, L Song, H Fang, J Tan, Y Zheng… - International …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease that occurs mainly in synovial
joints, causing synovial inflammation and joint injury. If diagnosed and treated in time, the …

Sex and age differences in sST2 in cardiovascular disease

DJ Beetler, KA Bruno, DN Di Florio… - Frontiers in …, 2023 - frontiersin.org
Aims The goal of this study was to determine whether sex and age differences exist for
soluble ST2 (sST2) for several cardiovascular diseases (CVDs). Methods We examined …