Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …

K+ channel principal subunits are by far the largest and most diverse of the ion channels.
This diversity originates partly from the large number of genes coding for K+ channel …

The properties and roles of ATP-sensitive (KATP) and inwardly rectifying (KIR) potassium
channels are reviewed. Potassium channels regulate the membrane potential of smooth …

▪ Abstract The past three years have seen remarkable progress in research on the molecular
basis of inward rectification, with significant implications for basic understanding and …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

About 10 distinct potassium channels in the heart are involved in shaping the action
potential. Some of the K+ channels are primarily responsible for early repolarization …

The inwardly rectifying potassium channel Kir4. 1 has been suggested to underlie the
principal K+ conductance of mammalian Müller cells and to participate in the generation of …

Glial cells express inwardly rectifying K+ (Kir) channels, which play a critical role in the
buffering of extracellular K+. Kir4. 1 is the only Kir channel so far shown to be expressed in …

Recent cloning of a family of genes encoding inwardly rectifying K+ channels has provided
the opportunity to explain some venerable problems in membrane biology. An expanding …

Background The transepithelial transport of electrolytes, solutes, and water in the kidney is a
well-orchestrated process involving numerous membrane transport systems. Basolateral …