Extensive investigation of gene fusions in cancer has led to the discovery of novel
biomarkers and therapeutic targets. To date, most studies have neglected chromosomal …

As a crucial kind of pervasive gene, long noncoding RNAs (lncRNAs) are abundant and key
players in brain function as well as numerous neurological disorders, especially ischemic …

Purpose Pancreatic adenocarcinoma (PAAD) remains a highly aggressive gastrointestinal
malignancy with a dismal prognosis. Pyroptosis has a key role in tumor development. Long …

Long non-coding RNAs (lncRNAs) are non-coding RNAs longer than 200 nucleotides with
dynamic regulatory functions. They interact with a wide range of molecules such as DNA …

Ewing sarcoma (ES) is a highly malignant primary bone tumor with poor prognosis. Studies
have shown that abnormal expression of lncRNA influences the prognosis of tumor patients …

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene
expression and different immune-related pathways. There is a great interest in identifying …

Background: Pyroptosis is a programmed death mode of inflammatory cells, which is closely
related to tumor progression and tumor immunity. Clear cell renal cell carcinoma (ccRCC) is …

As a non‐collinear expression form of genetic information, chimeric RNAs increase the
complexity of transcriptome in diverse organisms. Although chimeric RNAs have been …

We assess the performance of mRNA capture sequencing to identify fusion transcripts in
FFPE tissue of different sarcoma types, followed by RT-qPCR confirmation. To validate our …

Background It has previously been proven that circadian rhythm disruption is associated
with the incidence and deterioration of several tumors, which potentially leads to increased …