Breast cancer—epidemiology, risk factors, classification, prognostic markers, and current treatment strategies—an updated review

S Łukasiewicz, M Czeczelewski, A Forma, J Baj… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

LA Huppert, O Gumusay, D Idossa… - CA: a cancer journal for …, 2023 - Wiley Online Library
Hormone receptor (HR)‐positive and human epidermal growth factor receptor 2 (HER2)‐
negative breast cancer is defined by the presence of the estrogen receptor and/or the …

Breast cancer, version 3.2022, NCCN clinical practice guidelines in oncology

WJ Gradishar, MS Moran, J Abraham, R Aft… - Journal of the National …, 2022 - jnccn.org
The therapeutic options for patients with noninvasive or invasive breast cancer are complex
and varied. These NCCN Clinical Practice Guidelines for Breast Cancer include …

[HTML][HTML] Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

H Pan, R Peto, AMH Restrepo, MP Preziosi… - The Lancet, 2022 - Elsevier
Summary Background The Solidarity trial among COVID-19 inpatients has previously
reported interim mortality analyses for four repurposed antiviral drugs. Lopinavir …

[HTML][HTML] 21-gene assay to inform chemotherapy benefit in node-positive breast cancer

K Kalinsky, WE Barlow, JR Gralow… - … England Journal of …, 2021 - Mass Medical Soc
Background The recurrence score based on the 21-gene breast-cancer assay has been
clinically useful in predicting a chemotherapy benefit in hormone-receptor–positive, human …

Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology

WJ Gradishar, MS Moran, J Abraham… - Journal of the National …, 2024 - jnccn.org
Breast cancer is treated with a multidisciplinary approach involving surgical oncology,
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …

Assessment of Ki67 in breast cancer: updated recommendations from the international Ki67 in breast cancer working group

TO Nielsen, SCY Leung, DL Rimm… - JNCI: Journal of the …, 2021 - academic.oup.com
Abstract Ki67 immunohistochemistry (IHC), commonly used as a proliferation marker in
breast cancer, has limited value for treatment decisions due to questionable analytical …

The lingering mysteries of metastatic recurrence in breast cancer

AI Riggio, KE Varley, AL Welm - British journal of cancer, 2021 - nature.com
Despite being the hallmark of cancer that is responsible for the highest number of deaths,
very little is known about the biology of metastasis. Metastatic disease typically manifests …

Repurposed antiviral drugs for Covid-19—interim WHO solidarity trial results

WHO Solidarity Trial Consortium - New England journal of …, 2021 - Mass Medical Soc
Abstract Background World Health Organization expert groups recommended mortality trials
of four repurposed antiviral drugs—remdesivir, hydroxychloroquine, lopinavir, and interferon …

Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a …

R Bradley, J Braybrooke, R Gray, RK Hills, Z Liu… - The Lancet …, 2022 - thelancet.com
Background For women with early-stage oestrogen receptor (ER)-positive breast cancer,
adjuvant tamoxifen reduces 15-year breast cancer mortality by a third. Aromatase inhibitors …