Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Exocrine pancreatic insufficiency (EPI) is a condition caused by reduced or inappropriate
secretion or activity of pancreatic juice and its digestive enzymes, pancreatic lipase in …

Background & Aims In a 2010 randomized trial (the PANTER trial), a surgical step-up
approach for infected necrotizing pancreatitis was found to reduce the composite endpoint of …

Acute pancreatitis (AP) is an inflammatory disease that can progress to severe acute
pancreatitis (SAP), which increases the risk of death. AP is characterized by inappropriate …

Patients with acute pancreatitis (AP) often require ICU admission, especially when signs of
multiorgan failure are present, a condition that defines AP as severe. This disease is …

Background: Pain management is an important priority in the treatment of acute pancreatitis
(AP). Current evidence and guideline recommendations are inconsistent on the most …

Acute pancreatitis is the most common gastrointestinal indication for hospital admission, and
infected pancreatic and/or extrapancreatic necrosis is a potentially lethal complication …

Acute pancreatitis is a complex inflammatory disease with significant morbidity and mortality.
Despite advances in its management, the role of antibiotics in the prophylaxis and treatment …

Background: The effectiveness of prophylactic antibiotics in severe acute pancreatitis (SAP)
remains a debatable issue. This meta-analysis aimed to determine the efficacy of …

Objective This study was performed to systematically compare the safety and efficacy of total
enteral nutrition (TEN) and total parenteral nutrition (TPN) for patients with severe acute …