EANO guideline on the diagnosis and management of meningiomas

R Goldbrunner, P Stavrinou, MD Jenkinson… - Neuro …, 2021 - academic.oup.com
Meningiomas are the most common intracranial tumors. Yet, only few controlled clinical trials
have been conducted to guide clinical decision making, resulting in variations of …

FAPI PET/CT: will it end the hegemony of 18F-FDG in oncology?

RJ Hicks, PJ Roselt, KG Kallur, RW Tothill… - Journal of Nuclear …, 2021 - Soc Nuclear Med
For over 40 years, 18F-FDG has been the dominant PET tracer in neurology, cardiology,
inflammatory diseases, and, most particularly, oncology. Combined with the ability to …

[HTML][HTML] A vaccine targeting mutant IDH1 in newly diagnosed glioma

M Platten, L Bunse, A Wick, T Bunse, L Le Cornet… - Nature, 2021 - nature.com
Abstract Mutated isocitrate dehydrogenase 1 (IDH1) defines a molecularly distinct subtype of
diffuse glioma,–. The most common IDH1 mutation in gliomas affects codon 132 and …

Fibroblast activation protein–specific PET/CT imaging in fibrotic interstitial lung diseases and lung cancer: a translational exploratory study

M Röhrich, D Leitz, FM Glatting, AK Wefers… - Journal of nuclear …, 2022 - Soc Nuclear Med
Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …

[HTML][HTML] PET molecular imaging in drug development: the imaging and chemistry perspective

SG Nerella, P Singh, T Sanam, CS Digwal - Frontiers in Medicine, 2022 - frontiersin.org
The positron emission tomography (PET) with selective radioligands advances the drug
discovery and development process at the earlier and late stages by revealing information …

FET PET radiomics for differentiating pseudoprogression from early tumor progression in glioma patients post-chemoradiation

P Lohmann, MA Elahmadawy, R Gutsche, JM Werner… - Cancers, 2020 - mdpi.com
Simple Summary Following chemoradiation with alkylating agents in glioma patients,
structural magnetic resonance imaging (MRI) may suggest tumor progression which …

Artificial intelligence and machine learning in nuclear medicine: future perspectives

R Seifert, M Weber, E Kocakavuk, C Rischpler… - Seminars in nuclear …, 2021 - Elsevier
Artificial intelligence and machine learning based approaches are increasingly finding their
way into various areas of nuclear medicine imaging. With the technical development of new …

[HTML][HTML] Updates in IDH-wildtype glioblastoma

JM Melhem, J Detsky, MJ Lim-Fat, JR Perry - Neurotherapeutics, 2022 - Elsevier
Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021
WHO CNS5 classification has further stressed the importance of molecular signatures in …

A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study

HW Sim, KL McDonald, Z Lwin, EH Barnes… - Neuro …, 2021 - academic.oup.com
Background Temozolomide offers minimal benefit in patients with glioblastoma with
unmethylated O 6-methylguanine-DNA methyltransferase (MGMT) promoter status, hence …

Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …