Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy

C Ding, C Chen, X Zeng, H Chen, Y Zhao - ACS nano, 2022 - ACS Publications
Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

CR Powell, KM Dillon, JB Matson - Biochemical pharmacology, 2018 - Elsevier
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Y Zhang, J Fang, S Ye, Y Zhao, A Wang, Q Mao… - Nature …, 2022 - nature.com
Hydrogen sulfide (H2S) as an important biological gasotransmitter plays a pivotal role in
many physiological and pathological processes. The sensitive and quantitative detection of …

NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

C Jiang, H Huang, X Kang, L Yang, Z Xi… - Chemical Society …, 2021 - pubs.rsc.org
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …

BODIPY-based probes for the fluorescence imaging of biomolecules in living cells

T Kowada, H Maeda, K Kikuchi - Chemical Society Reviews, 2015 - pubs.rsc.org
Fluorescence imaging techniques have been widely used to visualize biological molecules
and phenomena. In particular, several studies on the development of small-molecule …

Structural modification strategies for the rational design of red/NIR region BODIPYs

H Lu, J Mack, Y Yang, Z Shen - Chemical Society Reviews, 2014 - pubs.rsc.org
This review focuses on classifying different types of long wavelength absorbing BODIPY
dyes based on the wide range of structural modification methods that have been adopted …

Near-Infrared Mitochondria-Targetable Fluorescent Probe for High-Contrast Bioimaging of H2S

S Gong, Z Zheng, X Guan, S Feng, G Feng - Analytical Chemistry, 2021 - ACS Publications
To elucidate the complex role of biological H2S and study the mitochondrial damage and
some related diseases, effective methods for visualization of H2S in mitochondria and in …

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes

X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Activity‐based sensing: a synthetic methods approach for selective molecular imaging and beyond

KJ Bruemmer, SWM Crossley… - Angewandte Chemie …, 2020 - Wiley Online Library
Emerging from the origins of supramolecular chemistry and the development of selective
chemical receptors that rely on lock‐and‐key binding, activity‐based sensing (ABS)—which …

Sensing and bioimaging of the gaseous signaling molecule hydrogen sulfide by near-infrared fluorescent probes

DA Jose, R Sakla, N Sharma, S Gadiyaram… - Acs …, 2020 - ACS Publications
A fluorescent probe for the monitoring of H2S levels in living cells and organisms is highly
desirable. In this regard, near-infrared (NIR) fluorescent probes have emerged as a …