Deep learning: new computational modelling techniques for genomics

G Eraslan, Ž Avsec, J Gagneur, FJ Theis - Nature Reviews Genetics, 2019 - nature.com
As a data-driven science, genomics largely utilizes machine learning to capture
dependencies in data and derive novel biological hypotheses. However, the ability to extract …

A guide to deep learning in healthcare

A Esteva, A Robicquet, B Ramsundar, V Kuleshov… - Nature medicine, 2019 - nature.com
Here we present deep-learning techniques for healthcare, centering our discussion on deep
learning in computer vision, natural language processing, reinforcement learning, and …

Opportunities and obstacles for deep learning in biology and medicine

T Ching, DS Himmelstein… - Journal of the …, 2018 - royalsocietypublishing.org
Deep learning describes a class of machine learning algorithms that are capable of
combining raw inputs into layers of intermediate features. These algorithms have recently …

Deep learning for healthcare: review, opportunities and challenges

R Miotto, F Wang, S Wang, X Jiang… - Briefings in …, 2018 - academic.oup.com
Gaining knowledge and actionable insights from complex, high-dimensional and
heterogeneous biomedical data remains a key challenge in transforming health care …

PlantPAN3. 0: a new and updated resource for reconstructing transcriptional regulatory networks from ChIP-seq experiments in plants

CN Chow, TY Lee, YC Hung, GZ Li… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Plant Promoter Analysis Navigator (PlantPAN; http://PlantPAN. itps. ncku. edu.
tw/) is an effective resource for predicting regulatory elements and reconstructing …

Deep learning for computational biology

C Angermueller, T Pärnamaa, L Parts… - Molecular systems …, 2016 - embopress.org
Technological advances in genomics and imaging have led to an explosion of molecular
and cellular profiling data from large numbers of samples. This rapid increase in biological …

Deep learning application pros and cons over algorithm deep learning application pros and cons over algorithm

AJ Moshayedi, AS Roy, A Kolahdooz… - EAI Endorsed Transactions …, 2022 - eudl.eu
Deep learning is a new area of machine learning research. Deep learning technology
applies the nonlinear and advanced transformation of model abstraction into a large …

[HTML][HTML] Methods for ChIP-seq analysis: A practical workflow and advanced applications

R Nakato, T Sakata - Methods, 2021 - Elsevier
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a central method in
epigenomic research. Genome-wide analysis of histone modifications, such as enhancer …

Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus

Y Zhang, L An, J Xu, B Zhang, WJ Zheng, M Hu… - Nature …, 2018 - nature.com
Although Hi-C technology is one of the most popular tools for studying 3D genome
organization, due to sequencing cost, the resolution of most Hi-C datasets are coarse and …

[HTML][HTML] Applied machine learning in cancer research: A systematic review for patient diagnosis, classification and prognosis

K Kourou, KP Exarchos, C Papaloukas… - Computational and …, 2021 - Elsevier
Artificial Intelligence (AI) has recently altered the landscape of cancer research and medical
oncology using traditional Machine Learning (ML) algorithms and cutting-edge Deep …