The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Human longevity has increased dramatically during the past century. More than 20% of the 9
billion population of the world will exceed the age of 60 in 2050. Since the last three …

Aging is a complex biological process characterized by a progressive decline in cellular and
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …

Fisetin has been shown to be beneficial for brain injury and age-related brain disease via
different mechanisms. The purpose of this study was to determine the presence of senescent …

Living organisms do not disregard the laws of thermodynamics and must therefore consume
energy for their survival. In this way, cellular energy exchanges, which aim above all at the …

Aging is the subject of many studies, facilitating the discovery of many interventions.
Epigenetic influences numerous life processes by regulating gene expression and also …

The purpose of the current study was to investigate the mechanism by which fisetin improves
atherosclerosis (AS) by regulating lipid metabolism and senescence in apolipoprotein E …

Aging-induced neurodegenerative diseases (NDs) are significantly increasing health
problem worldwide. It has been well documented that oxidative stress is one of the potential …

Human red blood cells (RBCs), senescent or damaged due to particular stress, can be
removed by programmed suicidal death, a process called eryptosis. There are various …