[HTML][HTML] Therapeutic potentials of superoxide dismutase
H Younus - International journal of health sciences, 2018 - ncbi.nlm.nih.gov
Superoxide dismutases (SODs) constitute a very important antioxidant defense against
oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive …
oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive …
Oxidative stress in liver pathophysiology and disease
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …
not only arise during metabolic functions but also during the biotransformation of …
Viral hijacking of cellular metabolism
This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …
that will be important for future studies to investigate. We discuss metabolic rewiring caused …
Viral hepatitis and liver cancer
M Ringehan, JA McKeating… - … Transactions of the …, 2017 - royalsocietypublishing.org
Hepatitis B and C viruses are a global health problem causing acute and chronic infections
that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the …
that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the …
Hepatocellular carcinoma pathogenesis: from genes to environment
PA Farazi, RA DePinho - Nature Reviews Cancer, 2006 - nature.com
Hepatocellular carcinoma is among the most lethal and prevalent cancers in the human
population. Despite its significance, there is only an elemental understanding of the …
population. Despite its significance, there is only an elemental understanding of the …
Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
Background & Aims: The mechanisms of liver injury in chronic hepatitis C virus (HCV)
infection are poorly understood. Indirect evidence suggests that oxidative stress and …
infection are poorly understood. Indirect evidence suggests that oxidative stress and …
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
Mice deficient in CuZn superoxide dismutase (CuZnSOD) showed no overt abnormalities
during development and early adulthood, but had a reduced lifespan and increased …
during development and early adulthood, but had a reduced lifespan and increased …
Role of free radicals in liver diseases
P Muriel - Hepatology international, 2009 - Springer
Reactive oxygen and nitrogen species (ROS and RNS) are produced by metabolism of
normal cells. However, in liver diseases, redox is increased thereby damaging the hepatic …
normal cells. However, in liver diseases, redox is increased thereby damaging the hepatic …
Redox mechanisms in hepatic chronic wound healing and fibrogenesis
E Novo, M Parola - Fibrogenesis & tissue repair, 2008 - Springer
Reactive oxygen species (ROS) generated within cells or, more generally, in a tissue
environment, may easily turn into a source of cell and tissue injury. Aerobic organisms have …
environment, may easily turn into a source of cell and tissue injury. Aerobic organisms have …
Molecular viral oncology of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the fifth most common cancer, but the third leading
cause of cancer death, in the world, with more than 500 000 fatalities annually. The major …
cause of cancer death, in the world, with more than 500 000 fatalities annually. The major …