In the past three decades invasive mycoses have globally emerged as a persistent source of
healthcare-associated infections. The cell wall surrounding the fungal cell opposes the …

Major events of the cell cycle—DNA synthesis, mitosis and cell division—are regulated by a
complex network of protein interactions that control the activities of cyclin‐dependent …

Cytokinesis is a temporally and spatially regulated process through which the cellular
constituents of the mother cell are partitioned into two daughter cells, permitting an increase …

A specialized cortical domain is organized by the septins at the necks of budding yeast cells.
Recent findings suggest that this domain serves as a diffusion barrier and also as a local cell …

A conserved signalling cascade—termed the mitotic-exit network in budding yeast and the
septation-initiation network in fission yeast—controls key events during exit from mitosis and …

▪ Abstract Cytokinesis creates two daughter cells endowed with a complete set of
chromosomes and cytoplasmic organelles. This conceptually simple event is mediated by a …

Cytokinesis is the final event of the cell division cycle, and its completion results in
irreversible partition of a mother cell into two daughter cells. Cytokinesis was one of the first …

Convergent evolution is common throughout the tree of life, but the molecular mechanisms
causing similar phenotypes to appear repeatedly are obscure. Yeasts have arisen in …

Abstract Background: In Saccharomyces cerevisiae the mitotic-exit network (MEN) functions
in anaphase to promote the release of the Cdc14p phosphatase from the nucleolus. This …

Saccharomyces cerevisiae chs2 mutants are unable to synthesize primary septum chitin,
and myo1 mutants cannot construct a functional contractile ring. The morphology of the two …