Polyurethanes (PUs) are a major family of polymers displaying a wide spectrum of physico-
chemical, mechanical and structural properties for a large range of fields. They have shown …

Tissue engineering often uses synthetic scaffolds to direct cell responses during engineered
tissue development. Since cells reside within specific niches of the extracellular matrix, it is …

Tissue engineering and regenerative medicine have emerged as innovative approaches to
enhance clinical outcomes by addressing tissue lesions and degenerations that can …

In tissue engineering, polyurethane-based implants have gained significant traction
because of their high compatibility and inertness. The implants therefore show fewer side …

Cardiac patches are biomaterials that can be used for transplantation and repair of
damaged myocardium by combining seed cells with the ability to form cardiomyocytes and …

Conventional tissue engineering, cell therapy, and current medical approaches were shown
to be successful in reducing mortality rate and complications caused by cardiovascular …

MicroRNAs (miRNAs) as therapeutic agents have attracted increasing interest in the past
decade owing to their significant effectiveness in treating a wide array of ailments. These …

Critical size bone defects represent a significant challenge worldwide, often leading to
persistent pain and physical disability that profoundly impact patients' quality of life and …

The mechanical match between synthetic scaffold and host tissue remains challenging in
tissue regeneration. The elastic soft tissues exhibit low initial moduli with a J-shaped tensile …

Challenging skeletal repairs are frequently seen in patients experiencing systemic
inflammation. To tackle the complexity and heterogeneity of the skeletal repair process, we …