Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and
inflammation in patients with arthritic conditions, and also acutely as analgesics by many …

Cancer is a leading cause of morbidity and mortality worldwide and the ratio of incidence is
increasing. Mortality usually results from recurrence or metastases. Surgical removal of the …

Novel series of celecoxib analogs endowed with benzofuran moiety 3a–e and 9a–d were
synthesized and evaluated for COX-1/COX-2 inhibitory activity in vitro. The most potent and …

Polypharmacology breaks up the classical paradigm of “one-drug, one target, one disease”
electing multitarget compounds as potential therapeutic tools suitable for the treatment of …

Simple Summary Diclofenac is a widely used drug for its anti-inflammatory and pain
alleviating properties. This review summarizes the current understanding about the drug …

Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively for analgesic and
antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers …

Saikosaponin a (SSa), the major triterpenoid saponin derivatives from Radix bupleuri (RB),
has been reported to have anti-inflammatory effects. The aim of this study was to investigate …

For more than 25 years, Dr. Charles Ciccone has been the forerunner in helping physical
therapists explore how medications affect patient rehabilitation. And he's been updating his …

The group of conjugated fatty acids known as conjugated linoleic acid (CLA) isomers have
been extensively studied with regard to their bioactive potential in treating some of the most …

New molecular hybrids combining benzothiophene or its bioisostere benzofuran with
rhodanine were synthesized as potential dual COX-2/5-LOX inhibitors. The benzothiophene …