The biology and role of CD44 in cancer progression: therapeutic implications

C Chen, S Zhao, A Karnad, JW Freeman - Journal of hematology & …, 2018 - Springer
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types
including cancer stem cells and frequently shows alternative spliced variants that are …

Fungal biodiversity and their role in soil health

M Frąc, SE Hannula, M Bełka, M Jędryczka - Frontiers in microbiology, 2018 - frontiersin.org
Soil health, and the closely related terms of soil quality and fertility, is considered as one of
the most important characteristics of soil ecosystems. The integrated approach to soil health …

Environmental stress destabilizes microbial networks

DJ Hernandez, AS David, ES Menges… - The ISME …, 2021 - academic.oup.com
Environmental stress is increasing worldwide, yet we lack a clear picture of how stress
disrupts the stability of microbial communities and the ecosystem services they provide …

Ecological memory of recurrent drought modifies soil processes via changes in soil microbial community

A Canarini, H Schmidt, L Fuchslueger, V Martin… - Nature …, 2021 - nature.com
Climate change is altering the frequency and severity of drought events. Recent evidence
indicates that drought may produce legacy effects on soil microbial communities. However, it …

High-throughput sequencing view on the magnitude of global fungal diversity

P Baldrian, T Větrovský, C Lepinay, P Kohout - Fungal Diversity, 2022 - Springer
High-throughput DNA sequencing has dramatically transformed several areas of biodiversity
research including mycology. Despite limitations, high-throughput sequencing is nowadays …

Scrutinizing key steps for reliable metabarcoding of environmental samples

A Alberdi, O Aizpurua, MTP Gilbert… - Methods in Ecology …, 2018 - Wiley Online Library
Metabarcoding of environmental samples has many challenges and limitations that require
carefully considered laboratory and analysis workflows to ensure reliable results. We …

Improved bacterial 16S rRNA gene (V4 and V4-5) and fungal internal transcribed spacer marker gene primers for microbial community surveys

W Walters, ER Hyde, D Berg-Lyons, G Ackermann… - Msystems, 2016 - Am Soc Microbiol
Designing primers for PCR-based taxonomic surveys that amplify a broad range of
phylotypes in varied community samples is a difficult challenge, and the comparability of …

FUNGuild: an open annotation tool for parsing fungal community datasets by ecological guild

NH Nguyen, Z Song, ST Bates, S Branco, L Tedersoo… - Fungal ecology, 2016 - Elsevier
Fungi typically live in highly diverse communities composed of multiple ecological guilds.
Although high-throughput sequencing has greatly increased the ability to quantify the …

Farm-like indoor microbiota in non-farm homes protects children from asthma development

PV Kirjavainen, AM Karvonen, RI Adams, M Täubel… - Nature medicine, 2019 - nature.com
Asthma prevalence has increased in epidemic proportions with urbanization, but growing up
on traditional farms offers protection even today. The asthma-protective effect of farms …

Dimensions of biodiversity in the Earth mycobiome

KG Peay, PG Kennedy, JM Talbot - Nature Reviews Microbiology, 2016 - nature.com
Fungi represent a large proportion of the genetic diversity on Earth and fungal activity
influences the structure of plant and animal communities, as well as rates of ecosystem …