The transmembrane proteins of the tetraspanin superfamily are implicated in a diverse
range of biological phenomena, including cell motility, metastasis, cell proliferation and …

Tetraspanins are membrane organizing proteins that play a role in organizing the cell
surface through the formation of subcellular domains consisting of tetraspanins and their …

Association of major histocompatibility complex (MHC) class II molecules with peptides
occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments …

Tetraspanin proteins form signaling complexes between them and with other membrane
proteins and modulate cell adhesion and migration properties. The surface expression of …

Human tetraspanin proteins are a group of 33 highly hydrophobic membrane proteins that
can form complexes in cholesterol‐rich microdomains, distinct from lipid rafts, on the cell …

CD151 (PETA-3/SFA-1) is a member of the transmembrane 4 superfamily (TM4SF) of cell-
surface proteins and is expressed abundantly both on the cell surface and in intracellular …

Tetraspanins regulate key processes in immune cells; however, the function of the leukocyte-
restricted tetraspanin CD53 is unknown. Here we show that CD53 is essential for …

The CD53 antigen is a tetraspanin protein of the lymphoid–myeloid lineage, but its
implication in biological effects is hardly known. Radioresistant tumor cells express very high …

Although the exact etiology of rheumatoid arthritis (RA) remains unknown, there is
increasing evidence that reactive oxygen species and a pro-oxidant/antioxidant imbalance …

The superfamily of tetraspanins comprises a group of polypeptides with four transmembrane
domains that form large supramolecular structures in the plasma membrane through their …