[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19

A Banerjee, SJ Czinn, RJ Reiter, TG Blanchard - Life sciences, 2020 - Elsevier
The outbreak of COVID-19 caused by 2019–nCov/SARS-CoV-2 has become a pandemic
with an urgent need for understanding the mechanisms and identifying a treatment. Viral …

Identification of natural inhibitors against prime targets of SARS-CoV-2 using molecular docking, molecular dynamics simulation and MM-PBSA approaches

A Sharma, J Vora, D Patel, S Sinha… - Journal of …, 2022 - Taylor & Francis
The recently emerged COVID-19 has been declared a pandemic by the World Health
Organization as to date; no therapeutic drug/vaccine is available for the treatment. Due to …

[HTML][HTML] A timely review of cross-kingdom regulation of plant-derived MicroRNAs

D Li, J Yang, Y Yang, J Liu, H Li, R Li, C Cao… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) belong to a class of non-coding RNAs that suppress gene expression
by complementary oligonucleotide binding to the sites in target messenger RNAs …

Nimbolide, a neem limonoid, is a promising candidate for the anticancer drug arsenal

S Nagini, R Nivetha, M Palrasu… - Journal of medicinal …, 2021 - ACS Publications
Nimbolide, a major limonoid constituent of Azadirachta indica, commonly known as neem,
has attracted increasing research attention owing to its wide spectrum of pharmacological …

Pharmacophore modeling, molecular docking and molecular dynamics simulation for screening and identifying anti-dengue phytocompounds

J Vora, S Patel, M Athar, S Sinha… - Journal of …, 2020 - Taylor & Francis
Dengue is a fast spreading mosquito borne viral disease that poses a serious threat to
human health. Lack of therapeutic drugs and vaccines signify that more resources need to …

[HTML][HTML] In silico approach in reveal traditional medicine plants pharmacological material basis

F Yi, L Li, L Xu, H Meng, Y Dong, H Liu, P Xiao - Chinese medicine, 2018 - Springer
In recent years, studies of traditional medicinal plants have gradually increased worldwide
because the natural sources and variety of such plants allow them to complement modern …

[HTML][HTML] Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: a target based networking …

D Wang, F Ali, H Liu, Y Cheng, M Wu… - Frontiers in …, 2022 - frontiersin.org
The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological
changes during the development of hypertensive vascular remodeling. Although quercetin …

Phytochemicals as sources of drugs

SM Ezzat, J Jeevanandam, C Egbuna, S Kumar… - … : An in-silico and in-vitro …, 2019 - Springer
Medicinal plants are known to contain substances which could be useful for the treatment of
diseases or for the production of drugs. These substances occur naturally in plants (leaves …

[HTML][HTML] Systematic elucidation of the mechanism of genistein against pulmonary hypertension via network pharmacology approach

Y Chen, D Chen, S Liu, T Yuan, J Guo, L Fang… - International Journal of …, 2019 - mdpi.com
Numerous studies have shown that genistein has a good therapeutic effect on pulmonary
hypertension (PH). However, there has been no systematic research performed yet to …