Immunological factors linked to geographical variation in vaccine responses
MMAR van Dorst, JJ Pyuza, G Nkurunungi… - Nature Reviews …, 2024 - nature.com
Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …
hampered by considerable variation in efficacy across populations and geographical …
Controlled human infection models to accelerate vaccine development
RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
Malaria vaccine efficacy, safety, and community perception in Africa: a scoping review of recent empirical studies
Aim The review summarizes the recent empirical evidence on the efficacy, safety, and
community perception of malaria vaccines in Africa. Methods Academic Search Complete …
community perception of malaria vaccines in Africa. Methods Academic Search Complete …
Correlates of malaria vaccine efficacy
DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction: An effective vaccine against malaria forms a global health priority. Both
naturally acquired immunity and sterile protection induced by irradiated sporozoite …
naturally acquired immunity and sterile protection induced by irradiated sporozoite …
Eosinophils, basophils and myeloid-derived suppressor cells in chronic Loa loa infection and its treatment in an endemic setting
G Burger, R Adamou, R Kreuzmair… - PLOS Neglected …, 2024 - journals.plos.org
Background Chronic infection by Loa loa remains an unsolved immunological paradox.
Despite harboring subcutaneously migrating adult worms and often high densities of …
Despite harboring subcutaneously migrating adult worms and often high densities of …
A CAF01-adjuvanted whole asexual blood-stage liposomal malaria vaccine induces a CD4+ T-cell-dependent strain-transcending protective immunity in rodent …
WA Okoth, MF Ho, M Zaman, E Cooper, P Som… - Mbio, 2023 - Am Soc Microbiol
Malaria is a leading cause of illness and death in children under 5 years of age in Sub-
Saharan Africa. Currently, there is no highly efficacious malaria vaccine capable of inducing …
Saharan Africa. Currently, there is no highly efficacious malaria vaccine capable of inducing …
Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases
S Rashidi, C Vieira, R Tuteja, R Mansouri… - Biomolecules, 2022 - mdpi.com
Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with
immune-regulatory properties in cancers and infectious diseases, presents both membrane …
immune-regulatory properties in cancers and infectious diseases, presents both membrane …
Antibody response to malaria vaccine candidates in pregnant women with Plasmodium falciparum and Schistosoma haematobium infections
Malaria in pregnancy has severe consequences for the mother and foetus. Antibody
response to specific malaria vaccine candidates (MVC) has been associated with a …
response to specific malaria vaccine candidates (MVC) has been associated with a …
Evaluation of serum soluble HLA-G levels post-recovery from COVID-19 and post-vaccination (Sinopharm and Pfizer-BioNTech)
RM Hamed, MM Mahmood, AH Ad'hiah - Human Immunology, 2023 - Elsevier
Abstract Serum soluble HLA-G (sHLA-G) levels have been shown to be upregulated in
COVID-19 patients. In this study, sHLA-G levels were examined in COVID-19 patients 14–21 …
COVID-19 patients. In this study, sHLA-G levels were examined in COVID-19 patients 14–21 …
[HTML][HTML] Safety, tolerability, and parasite clearance kinetics in controlled human malaria infection after direct venous inoculation of plasmodium falciparum sporozoites …
MF Chughlay, S Chalon, M El Gaaloul… - The American Journal …, 2022 - ncbi.nlm.nih.gov
Plasmodium falciparum sporozoite (PfSPZ) direct venous inoculation (DVI) using
cryopreserved, infectious PfSPZ (PfSPZ Challenge [Sanaria, Rockville, Maryland]) is an …
cryopreserved, infectious PfSPZ (PfSPZ Challenge [Sanaria, Rockville, Maryland]) is an …