Reactive nitrogen species (RNS) are various nitric oxide–derived compounds, including
nitroxyl anion, nitrosonium cation, higher oxides of nitrogen, S-nitrosothiols, and dinitrosyl …

Heme proteins are crucial for biological systems by performing diverse functions. Nature has
evolved diverse approaches to fine-tune the structure and function of heme proteins, of …

Background: Although exercise training has beneficial effects on skeletal muscle
bioenergetics and exercise performance in patients with severe chronic obstructive …

Globins constitute a superfamily of proteins widespread in all kingdoms of life, where they
fulfill multiple functions, such as efficient O2 transport and modulation of nitric oxide …

Tyrosine nitration, often observed during neurodegenerative disorders under nitrative stress,
is usually considered to be induced chemically either by nitric oxide and oxygen forming …

NGB (human neuroglobin), a recently discovered haem protein of the globin family
containing a six-co-ordinated haem, is expressed in nervous tissue, but the physiological …

Heme proteins perform a large array of biological functions using the same heme cofactor. A
primary method of regulating these diverse functions is the heme-protein cross-link, an …

Background: Nitric oxide (NO) and its metabolites can nitrosylate hemoglobin (Hb) through
the heme iron. Nitrihemoglobin (nitriHb) can be formed as result of porphyrin vinyl group …

Both β-amyloid (Aβ) peptides and oxidative stress conditions play key roles in Alzheimer's
disease. Hemin contributes to the development of the disease as it possesses redox …

Haptoglobin (Hp) binds free hemoglobin (Hb) dimers to prevent negative consequences of
Hb circulation in the extracellular environment. Although both monomeric Hb and myoglobin …