Weight loss as a predictor of cancer in primary care: a systematic review and meta-analysis

BD Nicholson, W Hamilton, J O'Sullivan… - British Journal of …, 2018 - bjgp.org
Background Weight loss is a non-specific cancer symptom for which there are no clinical
guidelines about investigation in primary care. Aim To summarise the available evidence on …

Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records

J Watson, C Salisbury, J Banks, P Whiting… - British journal of …, 2019 - nature.com
Background Early identification of cancer in primary care is important and challenging. This
study examined the diagnostic utility of inflammatory markers (C-reactive protein, erythrocyte …

Consultations for clinical features of possible cancer and associated urgent referrals before and during the COVID-19 pandemic: an observational cohort study from …

BD Nicholson, JM Ordóñez-Mena, S Lay-Flurrie… - British journal of …, 2022 - nature.com
Background It remains unclear to what extent reductions in urgent referrals for suspected
cancer during the COVID-19 pandemic were the result of fewer patients attending primary …

Is omission of free text records a possible source of data loss and bias in Clinical Practice Research Datalink studies? A case–control study

SJ Price, SA Stapley, E Shephard, K Barraclough… - BMJ open, 2016 - bmjopen.bmj.com
Objectives To estimate data loss and bias in studies of Clinical Practice Research Datalink
(CPRD) data that restrict analyses to Read codes, omitting anything recorded as text. Design …

Comorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records

LTA Mounce, S Price, JM Valderas… - British journal of cancer, 2017 - nature.com
Background: Pre-existing non-cancer conditions may complicate and delay colorectal
cancer diagnosis. Method: Incident cases (aged⩾ 40 years, 2007–2009) with colorectal …

Recognising laryngeal cancer in primary care: a large case–control study using electronic records

EA Shephard, MAL Parkinson, WT Hamilton - British Journal of General …, 2019 - bjgp.org
Background Over 1700 people are diagnosed with laryngeal cancer annually in England.
Current National Institute for Health and Care Excellence (NICE) guidelines on referral for …

Disease-related factors affecting timely lymphoma diagnosis: a qualitative study exploring patient experiences

DA Howell, RI Hart, AG Smith, U Macleod… - British Journal of …, 2019 - bjgp.org
Background Expediting cancer diagnosis is widely perceived as one way to improve patient
outcomes. Evidence indicates that lymphoma diagnosis is often delayed, yet understanding …

Risk factors and time to symptomatic presentation in leukaemia, lymphoma and myeloma

DA Howell, F Warburton, AJ Ramirez, E Roman… - British journal of …, 2015 - nature.com
Background: UK policy aims to improve cancer outcomes by promoting early diagnosis,
which for many haematological malignancies is particularly challenging as the pathways …

The determinants and impact of diagnostic delay in lymphoma in a TB and HIV endemic setting

K Antel, C Levetan, Z Mohamed, VJ Louw… - BMC cancer, 2019 - Springer
Background Little is known about the pathway to diagnosis of lymphoma in Sub-Saharan
Africa, despite the increased risk of lymphoma in people living with HIV (PLHIV). The …

Time to diagnosis and associated costs of an outpatient vs inpatient setting in the diagnosis of lymphoma: a retrospective study of a large cohort of major lymphoma …

X Bosch, C Sanclemente-Ansó, O Escoda, E Monclús… - BMC cancer, 2018 - Springer
Background Mainly because of the diversity of clinical presentations, diagnostic delays in
lymphoma can be excessive. The time spent in primary care before referral to the specialist …