Cancer PRSweb: an online repository with polygenic risk scores for major cancer traits and their evaluation in two independent biobanks
To facilitate scientific collaboration on polygenic risk scores (PRSs) research, we created an
extensive PRS online repository for 35 common cancer traits integrating freely available …
extensive PRS online repository for 35 common cancer traits integrating freely available …
[HTML][HTML] Melanoma susceptibility: an update on genetic and epigenetic findings
Malignant melanoma is one of the most highly ranked cancers in terms of years of life lost.
Hereditary melanoma with its increased familial susceptibility is thought to affect up to 12 …
Hereditary melanoma with its increased familial susceptibility is thought to affect up to 12 …
Bench research informed by GWAS results
NV Kondratyev, MV Alfimova, AK Golov, VE Golimbet - Cells, 2021 - mdpi.com
Scientifically interesting as well as practically important phenotypes often belong to the
realm of complex traits. To the extent that these traits are hereditary, they are usually 'highly …
realm of complex traits. To the extent that these traits are hereditary, they are usually 'highly …
Metrics for evaluating polygenic risk scores
SG Baker - JNCI cancer spectrum, 2021 - academic.oup.com
There is growing interest in the use of polygenic risk scores based on genetic variants to
predict cancer incidence. The type of metric used to evaluate the predictive performance of …
predict cancer incidence. The type of metric used to evaluate the predictive performance of …