Molecular imaging in oncology: Current impact and future directions

SP Rowe, MG Pomper - CA: a cancer journal for clinicians, 2022 - Wiley Online Library
The authors define molecular imaging, according to the Society of Nuclear Medicine and
Molecular Imaging, as the visualization, characterization, and measurement of biological …

[HTML][HTML] Magnetic resonance imaging (MRI) and MR spectroscopic methods in understanding breast cancer biology and metabolism

U Sharma, NR Jagannathan - Metabolites, 2022 - mdpi.com
A common malignancy that affects women is breast cancer. It is the second leading cause of
cancer-related death among women. Metabolic reprogramming occurs during cancer …

Hyperpolarized carbon-13 MRI for early response assessment of neoadjuvant chemotherapy in breast cancer patients

R Woitek, MA McLean, S Ursprung, OM Rueda… - Cancer research, 2021 - AACR
Hyperpolarized 13C-MRI is an emerging tool for probing tissue metabolism by measuring
13C-label exchange between intravenously injected hyperpolarized [1–13C] pyruvate and …

[HTML][HTML] Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study

S Ursprung, R Woitek, MA McLean, AN Priest… - Cancers, 2022 - mdpi.com
Simple Summary We evaluated renal cancer with varying aggressive appearances on
histology, using an emerging form of non-invasive metabolic MRI. This imaging technique …

[HTML][HTML] Hyperpolarized MRI–An update and future perspectives

SH Jørgensen, N Bøgh, ESS Hansen… - Seminars in Nuclear …, 2022 - Elsevier
In recent years, hyperpolarized 13 C magnetic resonance spectroscopic (MRS) imaging has
emerged as a complementary metabolic imaging approach. Hyperpolarization via …

Hyperpolarized carbon 13 MRI: clinical applications and future directions in oncology

SS Deen, C Rooney, A Shinozaki, J McGing… - Radiology: Imaging …, 2023 - pubs.rsna.org
Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …

[HTML][HTML] Comprehensive literature review of hyperpolarized carbon-13 MRI: the road to clinical application

M Vaeggemose, R F. Schulte, C Laustsen - Metabolites, 2021 - mdpi.com
This review provides a comprehensive assessment of the development of hyperpolarized
(HP) carbon-13 metabolic MRI from the early days to the present with a focus on clinical …

Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo

PCM van Zijl, K Brindle, H Lu, PB Barker… - Current opinion in …, 2021 - Elsevier
Access to metabolic information in vivo using magnetic resonance (MR) technologies has
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …

[HTML][HTML] Staging breast cancer with MRI, the T. A key role in the neoadjuvant setting

C Panico, F Ferrara, R Woitek, A D'Angelo, V Di Paola… - Cancers, 2022 - mdpi.com
Simple Summary Neoadjuvant chemotherapy (NACT) indications have expanded from
inoperable locally advanced to early-stage breast cancer. The pivotal role of magnetic …

[HTML][HTML] Metabolic imaging across scales reveals distinct prostate cancer phenotypes

N Sushentsev, G Hamm, L Flint, D Birtles… - Nature …, 2024 - nature.com
Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a
clinical tool for detecting and characterising prostate cancer. Here we use a range of …