[HTML][HTML] Menstruation: science and society

HOD Critchley, E Babayev, SE Bulun, S Clark… - American journal of …, 2020 - Elsevier
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

[HTML][HTML] Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

[HTML][HTML] Endometriosis and medical therapy: from progestogens to progesterone resistance to GnRH antagonists: a review

J Donnez, MM Dolmans - Journal of Clinical Medicine, 2021 - mdpi.com
Background: The first objective of this review was to present, based on recent literature, the
most frequently applied medical options (oral contraceptive pills (OCPs) and progestogens) …

[HTML][HTML] Stigma and endometriosis: a brief overview and recommendations to improve psychosocial well-being and diagnostic delay

OT Sims, J Gupta, SA Missmer, IO Aninye - International journal of …, 2021 - mdpi.com
Endometriosis is a chronic gynecological disease that affects approximately 1 in 10 women
of reproductive age. Symptoms of severe pelvic pain, infertility, fatigue, and abnormal …

[HTML][HTML] Endometrial stromal cell ferroptosis promotes angiogenesis in endometriosis

G Li, Y Lin, Y Zhang, N Gu, B Yang, S Shan, N Liu… - Cell death …, 2022 - nature.com
Endometriosis, a chronic disorder characterised by the presence of endometrial-like tissue
outside the uterus, is associated with iron overload and oxidative stress in the lesion …

[HTML][HTML] Systematic review and meta-analysis of incidence and prevalence of endometriosis

A Sarria-Santamera, B Orazumbekova, M Terzic… - Healthcare, 2020 - mdpi.com
There is still much controversy regarding the epidemiology of endometriosis. The objective
of this work is to conduct a systematic review, and if possible, proceed with a meta-analysis …

[HTML][HTML] The role of peritoneal macrophages in endometriosis

TN Ramírez-Pavez, M Martínez-Esparza… - International Journal of …, 2021 - mdpi.com
Endometriosis is an estrogen-dependent gynecological disorder, defined as the growth of
endometrial stromal cells and glands at extrauterine sites. Endometriotic lesions are more …

[HTML][HTML] Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis

AJ Shih, RP Adelson, H Vashistha, H Khalili, A Nayyar… - BMC medicine, 2022 - Springer
Background Endometriosis is a common, complex disorder which is underrecognized and
subject to prolonged delays in diagnosis. It is accompanied by significant changes in the …

Linzagolix: a new GnRH-antagonist under investigation for the treatment of endometriosis and uterine myomas

S Dababou, S Garzon, AS Laganà… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Uterine myomas and endometriosis are benign hormone-dependent diseases
affecting women of reproductive age. Substantial efforts have been made to develop …