Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

During adolescence, both rodent and human studies have revealed dynamic changes in the
developmental trajectories of corticolimbic structures, which are known to contribute to the …

Monoacylglycerol lipase (MAGL) has been characterized as the main enzyme responsible
for the inactivation of the most abundant brain endocannabinoid, 2-arachidonoylglycerol (2 …

Radiolabelling small molecules with beta-emitters has been intensively explored in the last
decades and novel concepts for the introduction of radionuclides continue to be reported …

The endocannabinoid system (ECS) is involved in a wide range of biological functions and
comprises cannabinoid receptors and enzymes responsible for endocannabinoid synthesis …

Despite numerous prevention methodologies and treatment options, hepatocellular
carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent …

Various preclinical and clinical studies exhibited the potential of cannabis against various
diseases, including cancer and related pain. Subsequently, many efforts have been made to …

Over the past decade there has been a surge of interest in the development of
endocannabinoid-based therapeutic approaches for the treatment of diverse …

Monoacylglycerol lipase (MAGL) is one of the key enzymes in the endocannabinoid system.
Inhibition of MAGL has been proposed as an attractive approach for the treatment of various …