Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

I Hanukoglu, A Hanukoglu - Gene, 2016 - Elsevier
The epithelial sodium channel (ENaC) is composed of three homologous subunits and
allows the flow of Na+ ions across high resistance epithelia, maintaining body salt and water …

Molecular mechanisms of adaptive evolution in wild animals and plants

Y Hu, X Wang, Y Xu, H Yang, Z Tong, R Tian… - Science China Life …, 2023 - Springer
Wild animals and plants have developed a variety of adaptive traits driven by adaptive
evolution, an important strategy for species survival and persistence. Uncovering the …

Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans

K Lossow, S Hübner, N Roudnitzky, JP Slack… - Journal of Biological …, 2016 - ASBMB
One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations

M Huelsmann, N Hecker, MS Springer, J Gatesy… - Science …, 2019 - science.org
The transition from land to water in whales and dolphins (cetaceans) was accompanied by
remarkable adaptations. To reveal genomic changes that occurred during this transition, we …

The evolution of sour taste

HER Frank, K Amato, M Trautwein… - … of the Royal …, 2022 - royalsocietypublishing.org
The evolutionary history of sour taste has been little studied. Through a combination of
literature review and trait mapping on the vertebrate phylogenetic tree, we consider the …

Hundreds of genes experienced convergent shifts in selective pressure in marine mammals

M Chikina, JD Robinson, NL Clark - Molecular biology and …, 2016 - academic.oup.com
Mammal species have made the transition to the marine environment several times, and
their lineages represent one of the classical examples of convergent evolution in …

Bitter taste receptors: Genes, evolution and health

SP Wooding, VA Ramirez… - Evolution, Medicine, and …, 2021 - academic.oup.com
Bitter taste perception plays vital roles in animal behavior and fitness. By signaling the
presence of toxins in foods, particularly noxious defense compounds found in plants, it …

Fresh water skin disease in dolphins: a case definition based on pathology and environmental factors in Australia

PJ Duignan, NS Stephens, K Robb - Scientific Reports, 2020 - nature.com
A distinct ulcerative dermatitis known as “freshwater skin disease” is an emerging clinical
and pathological presentation in coastal cetaceans worldwide. In Australia, two remarkably …

The life aquatic: advances in marine vertebrate genomics

JL Kelley, AP Brown, NO Therkildsen… - Nature Reviews …, 2016 - nature.com
The ocean is hypothesized to be where life on earth originated, and subsequent
evolutionary transitions between marine and terrestrial environments have been key events …

Oxidative stress drives divergent evolution of the glutathione peroxidase (GPX) gene family in mammals

R Tian, Y Geng, Y Yang, I Seim, G Yang - Integrative zoology, 2021 - Wiley Online Library
The molecular basis for adaptations to extreme environments can now be understood by
interrogating the ever‐increasing number of sequenced genomes. Mammals such as …