Aromatic abietane diterpenoids: Their biological activity and synthesis
MA González - Natural Product Reports, 2015 - pubs.rsc.org
Covering: 1980s–2014 In this study, the biological properties of natural abietane-type
diterpenoids with an aromatic C ring are reviewed. An overview of the synthetic studies of …
diterpenoids with an aromatic C ring are reviewed. An overview of the synthetic studies of …
Antiviral profiling of C-18-or C-19-functionalized semisynthetic Abietane diterpenoids
MA González-Cardenete, D Hamulic… - Journal of Natural …, 2022 - ACS Publications
Viral infections affect several million patients annually. Although hundreds of viruses are
known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs …
known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs …
Anti-herpetic and anti-dengue activity of abietane ferruginol analogues synthesized from (+)-dehydroabietylamine
VC Roa-Linares, YM Brand, LS Agudelo-Gomez… - European journal of …, 2016 - Elsevier
Abstract The abietane-type diterpenoid (+)-ferruginol (1), a bioactive compound isolated
from several plants, has attracted much attention as consequence of its pharmacological …
from several plants, has attracted much attention as consequence of its pharmacological …
Bispericyclic Diels–Alder Dimerization of ortho‐Quinols in Natural Product (Bio)Synthesis: Bioinspired Chemical 6‐Step Synthesis of (+)‐Maytenone
PA Peixoto, M El Assal, I Chataigner… - Angewandte …, 2021 - Wiley Online Library
Many natural products of plant or microbial origins are derived from enzymatic dearomative
oxygenation of 2‐alkylphenolic precursors into 6‐alkyl‐6‐hydroxycyclohexa‐2, 4‐dienones …
oxygenation of 2‐alkylphenolic precursors into 6‐alkyl‐6‐hydroxycyclohexa‐2, 4‐dienones …
Recent advances in abietane/icetexane synthesis
J Kang, TQ Le, CH Oh - Tetrahedron Letters, 2022 - Elsevier
Developed synthetic strategies for abietane and icetexane diterpenoids during 2010-present
are described in this review. To date, the [6–6–6]-and [6–7–6]-tricyclic skeletons of …
are described in this review. To date, the [6–6–6]-and [6–7–6]-tricyclic skeletons of …
Discovery of novel bioactive tanshinones and carnosol analogues against breast cancer
MA González-Cardenete, N González-Zapata, L Boyd… - Cancers, 2023 - mdpi.com
Simple Summary Abietane diterpenoids are naturally occurring metabolites isolated from a
large variety of plants, and many display antitumor properties. Tanshinones are abietane …
large variety of plants, and many display antitumor properties. Tanshinones are abietane …
Antimalarial activity of abietane ferruginol analogues possessing a phthalimide group
MA González, J Clark, M Connelly, F Rivas - Bioorganic & medicinal …, 2014 - Elsevier
Abstract The abietane-type diterpenoid (+)-ferruginol, a bioactive compound isolated from
New Zealand's Miro tree (Podocarpus ferruginea), displays relevant pharmacological …
New Zealand's Miro tree (Podocarpus ferruginea), displays relevant pharmacological …
Enantioselective polyene cyclization catalyzed by a chiral Brønsted acid
L Fan, C Han, X Li, J Yao, Z Wang, C Yao… - Angewandte …, 2018 - Wiley Online Library
The first enantioselective polyene cyclization initiated by a BINOL‐derived chiral N‐
phosphoramide (NPA) catalyzed protonation of an imine is described. The ion‐pair formed …
phosphoramide (NPA) catalyzed protonation of an imine is described. The ion‐pair formed …
[HTML][HTML] Anti-Zika virus activity of several abietane-type ferruginol analogues
Abietane diterpenoids are naturally occurring plant metabolites with a broad spectrum of
biological effects including antibacterial, antileishmanial, antitumor, antioxidant, as well as …
biological effects including antibacterial, antileishmanial, antitumor, antioxidant, as well as …
Aromatic abietane diterpenoids: total syntheses and synthetic studies
MA González - Tetrahedron, 2015 - Elsevier
Natural products have attracted synthetic chemist's attention from an academic point of view
for a long time. However, natural product synthesis is still essential for confirming the …
for a long time. However, natural product synthesis is still essential for confirming the …