The human virome: assembly, composition and host interactions
G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
Clinical metagenomics
CY Chiu, SA Miller - Nature Reviews Genetics, 2019 - nature.com
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
Host-viral infection maps reveal signatures of severe COVID-19 patients
Viruses are a constant threat to global health as highlighted by the current COVID-19
pandemic. Currently, lack of data underlying how the human host interacts with viruses …
pandemic. Currently, lack of data underlying how the human host interacts with viruses …
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Bacteriophages are the most abundant members of the microbiota and have the potential to
shape gut bacterial communities. Changes to bacteriophage composition are associated …
shape gut bacterial communities. Changes to bacteriophage composition are associated …
Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid
S Miller, SN Naccache, E Samayoa… - Genome …, 2019 - genome.cshlp.org
Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been
successfully tested in proof-of-concept case studies in patients with acute illness of unknown …
successfully tested in proof-of-concept case studies in patients with acute illness of unknown …
Interactions between bacteriophage, bacteria, and the mammalian immune system
The human body is host to large numbers of bacteriophages (phages)–a diverse group of
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …
[HTML][HTML] The healthy human blood microbiome: fact or fiction?
The blood that flows perpetually through our veins and arteries performs numerous functions
essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates …
essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
Bacteriophage transcytosis provides a mechanism to cross epithelial cell layers
Bacterial viruses are among the most numerous biological entities within the human body.
These viruses are found within regions of the body that have conventionally been …
These viruses are found within regions of the body that have conventionally been …
Genomic analyses from non-invasive prenatal testing reveal genetic associations, patterns of viral infections, and Chinese population history
We analyze whole-genome sequencing data from 141,431 Chinese women generated for
non-invasive prenatal testing (NIPT). We use these data to characterize the population …
non-invasive prenatal testing (NIPT). We use these data to characterize the population …