Sleep and circadian rhythm disruption are frequently observed in patients with psychiatric
disorders and neurodegenerative disease. The abnormal sleep that is experienced by these …

Dementia with Lewy bodies (DLB) is the second most common type of degenerative
dementia following Alzheimer's disease (AD). DLB is clinically and pathologically related to …

Lipid rafts are cholesterol-and sphingomyelin-enriched microdomains that provide a highly
saturated and viscous physico-chemical microenvironment to promote protein-lipid and …

Parkinson's disease (PD) is a common, disabling, neurodegenerative disorder. In addition to
classical motor symptoms, non-motor features are now widely accepted as part of the clinical …

Visual spatial impairment is often an early symptom of neurodegenerative disease; however,
this multi-faceted domain of cognition is not well-assessed by most typical dementia …

Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB) are
neurodegenerative conditions sharing a disorder of α-synuclein metabolism. Temporal …

Background: Very few recent studies are available that compare caregiver burden, sleep
quality, and stress in caregivers of different types of dementia. We aimed to investigate …

BackgroundThe accurate clinical characterisation of mild cognitive impairment (MCI) is
becoming increasingly important. The aim of this study was to compare the neuropsychiatric …

Dementia with Lewy bodies (DLB) is the underlying aetiology of 10–15% of all cases of
dementia and as such is a clinically important diagnosis. In the past few years, substantial …

Abstract Study Objectives: To assess the longitudinal course of cognitive functions in a
cohort of patients with idiopathic REM sleep behavior disorder (iRBD). Design: Prospective …