Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia

AA Fola, Q He, S Xie, J Thimmapuram… - Communications …, 2024 - nature.com
Background Genomic surveillance is crucial for monitoring malaria transmission and
understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in …

Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar

SV Connelly, NF Brazeau, M Msellem, BE Ngasala… - Elife, 2024 - elifesciences.org
Background: The Zanzibar archipelago of Tanzania has become a low-transmission area for
Plasmodium falciparum. Despite being considered an area of pre-elimination for years …

Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected

KM Kimenyi, MY Akinyi, K Mwikali, T Gilmore… - BMC infectious …, 2024 - Springer
Background Cumulative malaria parasite exposure in endemic regions often results in the
acquisition of partial immunity and asymptomatic infections. There is limited information on …

Plasmodium falciparum genetic diversity and multiplicity of infection among asymptomatic and symptomatic malaria-infected individuals in Uganda

A Mwesigwa, M Ocan, B Cummings… - Tropical Medicine and …, 2024 - Springer
Background Plasmodium falciparum (P. falciparum) remains a significant public health
challenge globally, especially in sub-Saharan Africa (SSA), where it accounts for 99% of all …

Temporal changes in Plasmodium falciparum genetic diversity and multiplicity of infection across three areas of varying malaria transmission intensities in Uganda

A Mwesigwa, SM Kiwuwa, B Musinguzi… - Tropical Medicine and …, 2024 - Springer
Background Malaria is a significant public health challenge in Uganda, with Plasmodium
falciparum (P. falciparum) responsible for most of malaria infections. The high genetic …

[HTML][HTML] Genomics reveals heterogeneous Plasmodium falciparum transmission and population differentiation in Zambia and bordering countries

AA Fola, Q He, S Xie, J Thimmapuram, KP Bhide… - medRxiv, 2024 - ncbi.nlm.nih.gov
Genomic surveillance plays a critical role in monitoring malaria transmission and
understanding how the parasite adapts in response to interventions. We conducted genomic …

Development of a Plasmodium vivax biobank for functional ex vivo assays

R Dash, KM Skillman, L Pereira, A Mascarenhas… - Malaria Journal, 2023 - Springer
Background Plasmodium vivax is the second most prevalent cause of malaria yet remains
challenging to study due to the lack of a continuous in vitro culture system, highlighting the …

Understanding the carriage and transmission of non-typhoidal Salmonella infections in Kenya.

E Muthumbi - 2024 - researchonline.lshtm.ac.uk
Non-typhoidal Salmonellae (NTS) are responsible for enteric disease characterized by self-
limiting enterocolitis in most parts of the world. In Africa, however, they cause severe …

Dampak Kebiasaan Tidur Larut Malam dan Hubungannya terhadap Kejadian Malaria

A Ardiansa, E Ester - Journal of Telenursing (JOTING), 2023 - journal.ipm2kpe.or.id
Penelitian ini bertujuan untuk melihat dampak dari kebiasaan tidur larut malam dan
hubungannya dengan kejadian malaria. Metode penelitian ini menggunakan analitik …