Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
Galectin-3 and cancer stemness
P Nangia-Makker, V Hogan, A Raz - Glycobiology, 2018 - academic.oup.com
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-
acetyllactosamine residues, has been unique due to the regulatory roles it performs in …
acetyllactosamine residues, has been unique due to the regulatory roles it performs in …
[HTML][HTML] Immunosuppressive property of MSCs mediated by cell surface receptors
S Liu, F Liu, Y Zhou, B Jin, Q Sun, S Guo - Frontiers in immunology, 2020 - frontiersin.org
In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for
refractory inflammatory diseases and engineered MSCs have appeared on the market as …
refractory inflammatory diseases and engineered MSCs have appeared on the market as …
Dual IFN-γ/hypoxia priming enhances immunosuppression of mesenchymal stromal cells through regulatory proteins and metabolic mechanisms
The immunosuppressive capacity of human mesenchymal stromal cells (MSCs) renders
them promising candidates for treating diverse immune disorders. However, after hundreds …
them promising candidates for treating diverse immune disorders. However, after hundreds …
Dietary fiber as a wide pillar of colorectal cancer prevention and adjuvant therapy
LF Pedrosa, JP Fabi - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
Colorectal cancer is the third most incident and second most lethal type of cancer worldwide.
Lifestyle and dietary patterns are the key factors for higher disease development risk. The …
Lifestyle and dietary patterns are the key factors for higher disease development risk. The …
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption
Bone-resorbing osteoclasts mobilize proteolytic enzymes belonging to the matrix
metalloproteinase (MMP) family to directly degrade type I collagen, the dominant …
metalloproteinase (MMP) family to directly degrade type I collagen, the dominant …
Galectin‐3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease …
Therapies based on transplantation of mesenchymal stromal cells (MSC) hold promise for
the management of inflammatory disorders. In chronic Chagas disease cardiomyopathy …
the management of inflammatory disorders. In chronic Chagas disease cardiomyopathy …
[HTML][HTML] Role of MSC-derived galectin 3 in the AML microenvironment
PP Ruvolo, VR Ruvolo, JK Burks, YH Qiu… - … et Biophysica Acta (BBA …, 2018 - Elsevier
In acute myeloid leukemia (AML), high Galectin 3 (LGALS3) expression is associated with
poor prognosis. The role of LGALS3 derived from mesenchymal stromal cells (MSC) in the …
poor prognosis. The role of LGALS3 derived from mesenchymal stromal cells (MSC) in the …
[HTML][HTML] Construction of the panoptosis-related gene model and characterization of tumor microenvironment infiltration in hepatocellular carcinoma
X Shi, X Gao, W Liu, X Tang, J Liu, D Pan… - Oncology …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common fatal cancer worldwide, patients with
HCC have a high mortality rate and poor prognosis. PANoptosis is a novel discovery of …
HCC have a high mortality rate and poor prognosis. PANoptosis is a novel discovery of …
[HTML][HTML] Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3
A Paganelli, F Diomede, GD Marconi, J Pizzicannella… - Biomedicines, 2023 - mdpi.com
Galectin-3 (GAL-3) is a beta-galactoside binding lectin produced by mesenchymal stem
cells (MSCs) and other cell sources under inflammatory conditions. Several studies have …
cells (MSCs) and other cell sources under inflammatory conditions. Several studies have …