Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …

Parkinson's disease (PD) is a complicated neurodegenerative disease attributed to
multifactorial changes. However, its pathological mechanism remains undetermined …

Parkinson's disease (PD) is one of the world's fastest growing neurological disorders. Much
is unknown about PD-associated economic burdens in the United States (US) and other …

A randomized, double-blind, placebo-controlled, 52-week study (no. NCT03068468)
evaluated gosuranemab, an anti-tau monoclonal antibody, in the treatment of progressive …

Progressive supranuclear palsy (PSP) is a complex clinicopathologic disease with no
current cure or disease modulating therapies that can only be definitively confirmed at …

Abstract Background The Movement Disorder Society criteria for progressive supranuclear
palsy define diagnostic allocations, stratified by certainty levels and clinical predominance …

Tauopathies are both clinical and pathological heterogeneous disorders characterized by
neuronal and/or glial accumulation of misfolded tau protein. It is now well understood that …

Progressive supranuclear palsy (PSP) is an atypical parkinsonism with prominent 4R-tau
neuropathology, and the classical clinical phenotype is characterized by vertical …

Although commonly known as movement disorders, progressive supranuclear palsy (PSP)
and corticobasal syndrome (CBS) may present with changes in speech and language …

Background Differentiating progressive supranuclear palsy‐parkinsonism (PSP‐P) from
Parkinson's disease (PD) is clinically challenging. Objective This study aimed to develop an …