Inflammation induced by Bothrops asper venom

C Teixeira, Y Cury, V Moreira, G Picolo, F Chaves - Toxicon, 2009 - Elsevier
Inflammation is a major characteristic of envenomation by snakes from viperine and
crotaline species. Bothrops asper snake venom elicits, among other alterations, a …

Amplification of snake venom toxicity by endogenous signaling pathways

PE Bickler - Toxins, 2020 - mdpi.com
The active components of snake venoms encompass a complex and variable mixture of
proteins that produce a diverse, but largely stereotypical, range of pharmacologic effects and …

[图书][B] Handbook of venoms and toxins of reptiles

SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

A comprehensive view of the structural and functional alterations of extracellular matrix by snake venom metalloproteinases (SVMPs): Novel perspectives on the …

JM Gutiérrez, T Escalante, A Rucavado, C Herrera… - Toxins, 2016 - mdpi.com
Snake venom metalloproteinases (SVMPs) affect the extracellular matrix (ECM) in multiple
and complex ways. Previously, the combination of various methodological platforms …

Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology

JS Cavalcante, DEG de Almeida… - International Journal of …, 2023 - mdpi.com
Snakebite envenoming represents a major health problem in tropical and subtropical
countries. Considering the elevated number of accidents and high morbidity and mortality …

Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation

C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

[HTML][HTML] Polymorphonuclear neutrophil leukocytes in snakebite envenoming

JP Zuliani, AM Soares, JM Gutiérrez - Toxicon, 2020 - Elsevier
Polymorphonuclear neutrophils are the most abundant leukocytes in the blood and
constitute key components of the innate immunity. Upon infection or tissue damage …

[HTML][HTML] Batroxase, a new metalloproteinase from B. atrox snake venom with strong fibrinolytic activity

ACO Cintra, LGB De Toni, MA Sartim, JJ Franco… - Toxicon, 2012 - Elsevier
The structures and functional activities of metalloproteinases from snake venoms have been
widely studied because of the importance of these molecules in envenomation. Batroxase …

Biochemistry and toxicology of toxins purified from the venom of the snake Bothrops asper

Y Angulo, B Lomonte - Toxicon, 2009 - Elsevier
The isolation and study of individual snake venom components paves the way for a deeper
understanding of the pathophysiology of envenomings–thus potentially contributing to …

Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation

JL Bernardoni, LF Sousa, LS Wermelinger, AS Lopes… - PLoS …, 2014 - journals.plos.org
Snake venom metalloproteinases (SVMPs) are major components in most viperid venoms
that induce disturbances in the hemostatic system and tissues of animals envenomated by …