Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

The scavenger receptor, class B type 1 (SR-B1), is a multiligand membrane receptor protein
that functions as a physiologically relevant high-density lipoprotein (HDL) receptor whose …

Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

▪ Abstract Liver X receptors (LXRs) and farnesoid X receptor (FXR) are nuclear receptors
that function as intracellular sensors for sterols and bile acids, respectively. In response to …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Because cholesterol is a precursor for the synthesis of steroid hormones, steroidogenic
tissues have evolved multiple pathways to ensure adequate supplies of cholesterol. These …

Atherosclerosis is a complex disease in which many processes contribute to lesion
development. Yet, it is well accepted that high serum levels of low‐density lipoproteins (LDL) …

A key issue in the immune system is to generate specific cell types, often with opposing
activities. The mechanisms of differentiation and subtype specification of immune cells such …

Data suggest that intestinal carotenoid absorption is a facilitated process. The present study
was conducted to determine whether carotenoids and cholesterol share common pathways …