Zinc normalizes hepatic lipid handling via modulation of ADA/XO/UA pathway and caspase 3 signaling in highly active antiretroviral therapy-treated Wistar rats
Background Although highly active antiretroviral therapy (HAART) is effective in the
management of HIV, it has been reported to induce hepatic injury and non-alcoholic fatty …
management of HIV, it has been reported to induce hepatic injury and non-alcoholic fatty …
Multifunctional gallic acid self-assembled hydrogel for alleviation of ethanol-induced acute gastric injury
H Huang, Y Hou, L Chen, W He, X Wang… - International Journal of …, 2023 - Elsevier
Ethanol-induced acute gastric injury is a prevalent type of digestive tract ulcer, yet
conventional treatments strategies frequently encounter several limitations, such as poor …
conventional treatments strategies frequently encounter several limitations, such as poor …
Sodium acetate abates lead-induced sexual dysfunction by upregulating testosterone-dependent eNOS/NO/cGMP signaling and activating Nrf2/HO-1 in male Wistar …
EE Besong, PJ Ashonibare, TM Akhigbe… - Naunyn-Schmiedeberg's …, 2024 - Springer
Oxidative stress has been linked with lead toxicity, including lead-induced sexual
dysfunction. On the contrary, sodium acetate has been proven to exert antioxidant activity …
dysfunction. On the contrary, sodium acetate has been proven to exert antioxidant activity …
[HTML][HTML] Age-related cataract: GSTP1 ubiquitination and degradation by Parkin inhibits its anti-apoptosis in lens epithelial cells
A Wu, W Zhang, G Zhang, X Ding, L Kang… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Purpose Oxidative stress-induced apoptosis of lens epithelial cells (LECs) contributes to the
pathogenesis of age-related cataract (ARC). The purpose of this research is to underlie the …
pathogenesis of age-related cataract (ARC). The purpose of this research is to underlie the …
Involvement of microRNA/cystine/glutamate transporter in cold-stressed gastric mucosa injury
YC Yin, X Li, X Rao, YJ Li, J Du - Frontiers in Pharmacology, 2022 - frontiersin.org
Stress ulcers are complicated by severe trauma and other critical diseases, the mechanism
of which remains unclear. An increasing number of studies have shown that microRNAs …
of which remains unclear. An increasing number of studies have shown that microRNAs …
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway
S Liu, H Ji, T Zhang, J Huang, X Yin, J Zhang, P Wang… - Phytomedicine, 2025 - Elsevier
Background Gastric precancerous lesions (GPL) typically originates from chronic gastritis
(CG), and the changes in glycolysis mediated by the HIF-1α pathway during the progression …
(CG), and the changes in glycolysis mediated by the HIF-1α pathway during the progression …
[HTML][HTML] Sodium acetate prevents testicular damage in Wistar rats subjected to testicular ischaemia/reperfusion injury
EE Besong, RE Akhigbe - Experimental and Molecular Pathology, 2024 - Elsevier
Aims The aim of this study was to investigate the potential antioxidant, anti-inflammatory,
and sperm function-preserving properties of sodium acetate (ACE), a histone deacetylase …
and sperm function-preserving properties of sodium acetate (ACE), a histone deacetylase …
In Vitro Low-Bortezomib Doses Induce Apoptosis and Independently Decrease the Activities of Glutathione S-Transferase and Glutathione Peroxidase in Multiple …
S Zmorzynski, S Popek-Marciniec, B Biernacka… - Genes, 2024 - mdpi.com
Background: Multiple myeloma (MM) is a malignancy derived from plasma cells. Bortezomib
affects the concentration of reduced glutathione (GSH) and the activity of glutathione …
affects the concentration of reduced glutathione (GSH) and the activity of glutathione …