Adrenocortical carcinoma: Updates of clinical and pathological features after renewed world health organisation classification and pathology staging

AK Lam - Biomedicines, 2021 - mdpi.com
Adrenocortical carcinoma (ACC) is a heterogenous group of diseases with different clinical
behaviour between adult and paediatric patients. In addition, three histological variants …

The inferior vena cava: anatomical variants and acquired pathologies

SJ Li, J Lee, J Hall, TR Sutherland - Insights into imaging, 2021 - Springer
The inferior vena cava (IVC) is the largest vein in the body, draining blood from the
abdomen, pelvis and lower extremities. This pictorial review summarises normal anatomy …

[HTML][HTML] A pan-tissue survey of mosaic chromosomal alterations in 948 individuals

T Gao, ME Kastriti, V Ljungström, A Heinzel… - Nature …, 2023 - nature.com
Genetic mutations accumulate in an organism's body throughout its lifetime. While somatic
single-nucleotide variants have been well characterized in the human body, the patterns …

Pharmacological profile and effects of mitotane in adrenocortical carcinoma

CR Corso, A Acco, C Bach, SJR Bonatto… - British journal of …, 2021 - Wiley Online Library
Mitotane is the only adrenolytic drug approved by the Food and Drug Administration for
treating adrenocortical carcinoma (ACC). This drug has cytotoxic effects on tumour tissues; it …

American Association of Clinical Endocrinology Disease state clinical review on the evaluation and management of adrenocortical carcinoma in an adult: a practical …

K Kiseljak-Vassiliades, I Bancos, A Hamrahian… - Endocrine Practice, 2020 - Elsevier
Objective: The aim of this Disease State Clinical Review is to provide a practical approach to
patients with newly diagnosed adrenocortical carcinoma, as well as to follow-up and …

Adrenocortical carcinoma: current state of the art, ongoing controversies, and future directions in diagnosis and treatment

OA Shariq, TJ McKenzie - Therapeutic Advances in Chronic …, 2021 - journals.sagepub.com
Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with an annual incidence
of~ 1 case per million population. Differentiating between ACC and benign adrenocortical …

Preclinical models of adrenocortical cancer

AJH Sedlack, SJ Hatfield, S Kumar, Y Arakawa… - Cancers, 2023 - mdpi.com
Simple Summary Adrenocortical cancer is a very rare form of endocrine cancer with dismal
prognosis. Preclinical models such as cell lines, organoids, and mouse models are essential …

Current status and future targeted therapy in adrenocortical cancer

G Alyateem, N Nilubol - Frontiers in Endocrinology, 2021 - frontiersin.org
Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. The current
treatment standards include complete surgical resection for localized resectable disease …

Adrenal cortical carcinoma: pathology, genomics, prognosis, imaging features, and mimics with impact on management

AA Ahmed, AJ Thomas, DM Ganeshan, KJ Blair… - Abdominal …, 2020 - Springer
Adrenocortical carcinoma (ACC) is a rare tumor with a poor prognosis. Most tumors are
either metastatic or locally invasive at the time of diagnosis. Differentiation between ACC …

The who, when, and why of primary adrenal malignancies: Insights into the epidemiology of a rare clinical entity

T Chandrasekar, H Goldberg, Z Klaassen, CJD Wallis… - Cancer, 2019 - Wiley Online Library
Background Primary malignancies of the adrenal glands are rare. Epidemiologic
assessment of primary adrenal malignancies is lacking and has been limited to case reports …