The aortic wall is composed of highly dynamic cell populations and extracellular matrix. In
response to changes in the biomechanical environment, aortic cells and extracellular matrix …

Smoking is one of the most important preventable factors causing peripheral artery disease
(PAD). The purpose of this review is to comprehensively analyze and summarize the …

Aims The artery contains numerous cell types which contribute to multiple vascular
diseases. However, the heterogeneity and cellular responses of these vascular cells during …

Macrophages have a key functional role in the pathogenesis of various cardiovascular
diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the …

Objectives This study aimed to identify key AAA-related m1A RNA methylation regulators
and their association with immune infiltration in AAA. Furthermore, we aimed to explore the …

Abdominal aortic aneurysm (AAA) is a catastrophic disease with little effective therapy.
Myocardin related transcription factor A (MRTFA, MKL1) is a multifaceted transcription factor …

Vascular disease is the leading health problem worldwide. Vascular microenvironment
encompasses diverse cell types, including those within the vascular wall, blood cells …

Sex differences (biological distinctions between males and females) present a complex
interplay of genetic, developmental, biological, and environmental factors. More and more …

The cardiovascular field is still searching for a treatment for abdominal aortic aneurysms
(AAA). This inflammatory disease often goes undiagnosed until a late stage and associated …

Aortic aneurysm (AA) is a degenerative vascular disease that involves aortic dilatation, and,
if untreated, it can lead to rupture. Despite its significant impact on the healthcare system, its …