[HTML][HTML] SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

[HTML][HTML] Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

[HTML][HTML] ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

G Grasselli, CS Calfee, L Camporota, D Poole… - Intensive care …, 2023 - Springer
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the
European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

A new global definition of acute respiratory distress syndrome

MA Matthay, Y Arabi, AC Arroliga… - American journal of …, 2024 - atsjournals.org
Background: Since publication of the 2012 Berlin definition of acute respiratory distress
syndrome (ARDS), several developments have supported the need for an expansion of the …

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

C Cervia-Hasler, SC Brüningk, T Hoch, B Fan, G Muzio… - Science, 2024 - science.org
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …

[HTML][HTML] Convalescent plasma for covid-19–induced ARDS in mechanically ventilated patients

B Misset, M Piagnerelli, E Hoste… - … England Journal of …, 2023 - Mass Medical Soc
Background Passive immunization with plasma collected from convalescent patients has
been regularly used to treat coronavirus disease 2019 (Covid-19). Minimal data are …

[HTML][HTML] Oxygen-saturation targets for critically ill adults receiving mechanical ventilation

MW Semler, JD Casey, BD Lloyd… - … England Journal of …, 2022 - Mass Medical Soc
Background Invasive mechanical ventilation in critically ill adults involves adjusting the
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation …

[PDF][PDF] Living guidance for clinical management of COVID-19: living guidance, 23 November 2021

World Health Organization - 2021 - apps.who.int
This guideline is based on the above strategic priorities, and is intended for clinicians
involved in the care of patients with suspected or confirmed COVID-19. It is not meant to …

[HTML][HTML] Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation

LE Leard, AM Holm, M Valapour, AR Glanville… - The Journal of Heart and …, 2021 - Elsevier
Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral …