Reverse vaccinology approaches to design a potent multiepitope vaccine against the HIV whole genome: immunoinformatic, bioinformatics, and molecular dynamics …

A Hashempour, N Khodadad, S Akbarinia… - BMC infectious …, 2024 - Springer
Substantial advances have been made in the development of promising HIV vaccines to
eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes …

Design of multivalent-epitope vaccine models directed toward the world's population against HIV-Gag polyprotein: Reverse vaccinology and immunoinformatics

A Hashempour, N Khodadad, P Bemani, Y Ghasemi… - Plos one, 2024 - journals.plos.org
Significant progress has been made in HIV-1 research; however, researchers have not yet
achieved the objective of eradicating HIV-1 infection. Accordingly, in this study, eucaryotic …

Predictors of antiretroviral treatment failure to the first line therapy: a cross-sectional study among Iranian HIV-positive adults

A Hashempour, N Khodadad, R Ziaei, B Rezaei… - BMC Infectious …, 2024 - Springer
Background HIV virological failure is one of the main problems in HIV-infected patients, and
identifying the main predictors of such treatment failure may help in combating HIV/AIDS …

Interaction Between Vpx and SAMHD1, Vital for SAMHD1 Inhibition

Z Hasanshahi, B Dehghani… - AIDS Research and …, 2024 - liebertpub.com
It was confirmed that the sterile alpha motif and HD domain 1 (SAMHD1) limits human
immunodeficiency virus type 1 (HIV-1) replication. In contrast, viral protein x (Vpx) in HIV-2 …

[HTML][HTML] Transmitted drug resistance against integrase strand transfer inhibitors in Iranian HIV-Infected Naïve patients

A Hashempour, Z Musavi, J Moayedi… - Avicenna Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Human Immunodeficiency Virus (HIV) has claimed the lives of millions of
people during the past decades. While several antiretroviral drugs like Integrase Strand …

[HTML][HTML] Assessment of human Herpes Virus-8 infection in Iranian cirrhotic patients on the waiting list for liver transplantation: A cross-sectional analysis

J Moayedi, A Hashempour, Z Musavi, F Ghasabi… - New Microbes and New …, 2024 - Elsevier
Abstract Background Human Herpes Virus 8 (HHV-8) is involved in autoimmunity. However,
its association with advanced liver disease has not been fully explained. Herein, the …

Frequency of Fusion Inhibitor Resistance Mutations Among Therapy-Naïve HIV Patients

F Ghassabi, A Hashempour, B Dehghani… - AIDS Research and …, 2024 - liebertpub.com
Glycoprotein 41 (gp41) of the human immunodeficiency virus type 1 (HIV-1) protein plays a
critical role in membrane fusion. Gp41 binds to proteins in the plasma membrane of CD4+ T …

Unveiling Fv1's Potential: Insights into its Interaction with the HIV-1 Capsid

B Dehghani, A Hashempour - 2024 - researchsquare.com
Abstract Virus susceptibility factor 1 (Fv1) serves as the prototype restriction factor guarding
against infection by murine leukemia virus (MLV). Analysis of the Fv1 sequences revealed …