MRD is replacing morphology to measure treatment response in ALL and is being used, with
promising results, for risk-stratification in clinical protocols. Recent studies provide further …

Purpose: Although modern cure rates for childhood acute lymphoblastic leukemia (ALL)
exceed 80%, the outlook remains poor in patients with high-risk disease and those who …

Several studies have reported an association between the rapidity of reduction in peripheral
blood blast count or recovery of normal hematopoiesis and treatment outcome during …

Pediatric acute myeloid leukemia (AML) is a devastating disease with a high risk of relapse.
Current risk classification designates patients as high or low risk (LR) based on molecular …

BACKGROUND Absolute lymphocyte counts (ALC) during treatment have been associated
with outcome in children and adults with hematologic malignancies. However, the impact of …

Background: Accurate risk stratification is essential for successful treatment outcome in
childhood acute lymphoblastic leukemia. Early recovery of absolute lymphocyte count (ALC) …

Children with Down syndrome (DS) bear an increased risk of acute lymphoblastic leukemia
(ALL) and treatment complications. We compared blood counts and toxicities in 22 DS and …

Introduction: Children with newly diagnosed acute lymphoblastic leukemia (ALL) present
with low peripheral blood counts caused by bone marrow replacement. The recovery of …

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. While
frontline chemotherapy regimens are generally very effective, the prognosis for patients …

Recent studies have reported that the absolute lymphocyte count (ALC) during induction
therapy is predictive of treatment outcome in de novo acute lymphoblastic leukemia (ALL); …