Atherosclerotic cardiovascular disease (ASCVD) frequently results in sudden death and
poses a serious threat to public health worldwide. The drugs approved for the prevention …

One of the most cutting-edge, effective, and least invasive pharmaceutical innovations is the
utilization of microneedles (MNs) for drug delivery, patient monitoring, diagnostics, medicine …

Background Allicin, the principle active constituent in garlic, has been reported to have
antihypertensive effects on drug-induced hypertension or renal hypertension in rats, but …

A key feature of chronic heart failure (HF) is the sustained activation of endogenous
neurohormonal systems in response to impaired cardiac pumping and/or filling properties …

Hypertensive disorders of pregnancy are among the most serious conditions that pregnancy
care providers face; however, little attention has been paid to the concept of tailoring clinical …

Introduction Hydralazine is a vasodilator used to treat hypertension, pre-eclampsia, and
heart failure. The current article reviews the clinical pharmacokinetics (PK) of hydralazine …

Objective To characterize the drug-related problems (DRPs) in high-risk pregnant women
with hypertension and gestational diabetes mellitus according to frequency, type, cause, and …

Purpose To evaluate the association of tadalafil, a phosphodiesterase-5 inhibitor (PDE5I),
with major adverse cardiac events (MACE) or venous thromboembolism (VTE) in men with …

Resistant hypertension is defined as high blood pressure that remains uncontrolled despite
treatment with at least three antihypertensive drugs at adequate doses. Resistant …

The present systematic review and meta-analysis investigated the effects of hydralazine
compared with other antihypertensive drugs in maternal, perinatal and neonatal outcomes of …