Safety, tolerability, and risks associated with first-and second-generation antipsychotics: a state-of-the-art clinical review
M Solmi, A Murru, I Pacchiarotti… - … and clinical risk …, 2017 - Taylor & Francis
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
Non-alcoholic fatty liver disease (NAFLD) as a neglected metabolic companion of psychiatric disorders: common pathways and future approaches
Ó Soto-Angona, G Anmella, MJ Valdés-Florido… - BMC medicine, 2020 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis
in over 5% of the parenchyma in the absence of excessive alcohol consumption. It is more …
in over 5% of the parenchyma in the absence of excessive alcohol consumption. It is more …
Antidepressants-and antipsychotics-induced hepatotoxicity
N Todorović Vukotić, J Đorđević, S Pejić… - Archives of …, 2021 - Springer
Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical
presentations that can escalate to acute liver failure. The worldwide increase in the use of …
presentations that can escalate to acute liver failure. The worldwide increase in the use of …
Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: a critical review
H Xu, X Zhuang - Neuropsychiatric disease and treatment, 2019 - Taylor & Francis
The atypical antipsychotics (AAPs) have been used as first-line drugs in psychiatric practice
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …
Does the gut microbiome partially mediate the impact of air pollutants exposure on liver function? Evidence based on schizophrenia patients
W Yi, Y Ji, H Gao, R Pan, Q Wei, J Cheng, J Song… - Environmental …, 2021 - Elsevier
Air pollution may alter the composition of gut microbiome and subsequent liver-related
metabolic disorders. Schizophrenia was often accompanied by liver dysfunction. But it was …
metabolic disorders. Schizophrenia was often accompanied by liver dysfunction. But it was …
Intrinsic and antipsychotic drug-induced metabolic dysfunction in schizophrenia
Z Freyberg, D Aslanoglou, R Shah… - Frontiers in …, 2017 - frontiersin.org
For decades, there have been observations demonstrating significant metabolic
disturbances in people with schizophrenia including clinically relevant weight gain …
disturbances in people with schizophrenia including clinically relevant weight gain …
Predicting treatment resistance from first-episode psychosis using routinely collected clinical information
Around a quarter of people who experience a first episode of psychosis (FEP) will develop
treatment-resistant schizophrenia, but there are currently no established clinically useful …
treatment-resistant schizophrenia, but there are currently no established clinically useful …
Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case–control study
Cardiovascular diseases are the leading cause of death in schizophrenia. Patients with
schizophrenia show evidence of concentric cardiac remodelling (CCR), defined as an …
schizophrenia show evidence of concentric cardiac remodelling (CCR), defined as an …
Chronic treatment with the modified Longdan Xiegan Tang attenuates olanzapine-induced fatty liver in rats by regulating hepatic de novo lipogenesis and fatty acid …
L Ren, D Sun, X Zhou, Y Yang, X Huang, Y Li… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance The modified Longdan Xiegan Tang (mLXT) has
been used clinically for various neuropsychiatric disorders and liver diseases. The use of …
been used clinically for various neuropsychiatric disorders and liver diseases. The use of …
The bidirectional association of nonalcoholic fatty liver disease with depression, bipolar disorder, and schizophrenia
Nonalcoholic fatty liver disease (NAFLD) is a complex metabolic-inflammatory disease
associated with poor outcomes and decreased quality of life. NAFLD is overrepresented in …
associated with poor outcomes and decreased quality of life. NAFLD is overrepresented in …