The role of mitochondrial fission in cardiovascular health and disease

JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Dietary and physiological effects of zinc on the immune system

I Wessels, HJ Fischer, L Rink - Annual review of nutrition, 2021 - annualreviews.org
Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …

A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

PR Haynes, ES Pyfrom, Y Li, C Stein… - Nature …, 2024 - nature.com
Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …

[HTML][HTML] Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease

YJ Liu, RL McIntyre, GE Janssens… - Mechanisms of ageing …, 2020 - Elsevier
The mitochondria is the major hub to convert energy for cellular processes. Dysregulation of
mitochondrial function is one of the classical hallmarks of aging, and mitochondrial …

Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance

D Sun, J Wang, S Toan, D Muid, R Li, X Chang, H Zhou - Angiogenesis, 2022 - Springer
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

Mitophagy in tumorigenesis and metastasis

LP Poole, KF Macleod - Cellular and molecular life sciences, 2021 - Springer
Cells use mitophagy to remove dysfunctional or excess mitochondria, frequently in response
to imposed stresses, such as hypoxia and nutrient deprivation. Mitochondrial cargo …

Nutrient element decorated polyetheretherketone implants steer mitochondrial dynamics for boosted diabetic osseointegration

H Wang, X Fu, J Shi, L Li, J Sun, X Zhang… - Advanced …, 2021 - Wiley Online Library
As a chronic metabolic disease, diabetes mellitus (DM) creates a hyperglycemic micromilieu
around implants, resulting inthe high complication and failure rate of implantation because …

Regulation of mitochondrial ATP production: Ca2+ signaling and quality control

L Boyman, M Karbowski, WJ Lederer - Trends in molecular medicine, 2020 - cell.com
Cardiac ATP production primarily depends on oxidative phosphorylation in mitochondria
and is dynamically regulated by Ca 2+ levels in the mitochondrial matrix as well as by …

The function and regulation of zinc in the brain

RF Krall, T Tzounopoulos, E Aizenman - Neuroscience, 2021 - Elsevier
Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

SIRT5‐related Desuccinylation modification contributes to quercetin‐induced protection against heart failure and high‐glucose‐prompted cardiomyocytes injured …

X Chang, T Zhang, J Wang, Y Liu, P Yan… - Oxidative Medicine …, 2021 - Wiley Online Library
Myocardial fibrosis represents the primary pathological change associated with diabetic
cardiomyopathy and heart failure, and it leads to decreased myocardial compliance with …