Epigenetics refers to molecular factors and processes around DNA that can affect genome
activity and gene expression independent of DNA sequence. Epigenetic mechanisms drive …

Previous studies have discussed the importance of an optimal range of metabolic activity
during preimplantation development. To avoid factors than can trigger an undesirable …

In many cell types, epigenetic changes are partially regulated by the availability of
metabolites involved in the activity of chromatin-modifying enzymes. Even so, the …

Metabolic and molecular profiles were reported as different for bovine embryos with distinct
kinetics during the first cleavages. In this study, we used this same developmental model …

Background The timing of the first cell divisions may predict the developmental potential of
an embryo, including its ability to establish pregnancy. Besides differences related to …

Mesenchymal stem cells (MSCs) are multipotent cells which are popular in human
regenerative medicine. These cells can renew themselves and differentiate into several …

Este trabajo se basó en el hecho de que los embriones producidos In vitro son menos
competentes que los embriones generados In vivo. El objetivo de nuestra investigación fue …

Foram avaliados 7 transcritos de genes envolvidos na metilação (SETDB1, SETDB2,
SUV39H1, SUV39H2, EHMT1, EHMT2 e PRDM2) e 10 relacionados à desmetilação de …

O momento das primeiras divisões celulares pode predizer o potencial de desenvolvimento
de um embrião, incluindo sua capacidade de estabelecer prenhez. Além de diferenças …